A review of drug knowledge discovery using BioNLP and tensor or matrix decomposition.

Genomics & informatics Pub Date : 2019-06-01 Epub Date: 2019-06-27 DOI:10.5808/GI.2019.17.2.e18
Mina Gachloo, Yuxing Wang, Jingbo Xia
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引用次数: 11

Abstract

Prediction of the relations among drug and other molecular or social entities is the main knowledge discovery pattern for the purpose of drug-related knowledge discovery. Computational approaches have combined the information from different sources and levels for drug-related knowledge discovery, which provides a sophisticated comprehension of the relationship among drugs, targets, diseases, and targeted genes, at the molecular level, or relationships among drugs, usage, side effect, safety, and user preference, at a social level. In this research, previous work from the BioNLP community and matrix or matrix decomposition was reviewed, compared, and concluded, and eventually, the BioNLP open-shared task was introduced as a promising case study representing this area.

Abstract Image

使用BioNLP和张量或矩阵分解的药物知识发现综述。
预测药物与其他分子或社会实体之间的关系是毒品相关知识发现的主要知识发现模式。计算方法结合了来自不同来源和水平的信息,用于药物相关知识的发现,这在分子水平上提供了对药物、靶标、疾病和靶向基因之间关系的复杂理解,或在社会水平上提供对药物、用法、副作用、安全性和用户偏好之间关系的精细理解。在这项研究中,对BioNLP社区和矩阵或矩阵分解的先前工作进行了回顾、比较和总结,最终,BioNLP开放共享任务被引入,作为代表该领域的一个有前景的案例研究。
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