Genomics & informatics

In silico design and evaluation of a multiepitope vaccine against Bordetella pertussis: structural, immunological, and biological properties.

Pub Date : 2025-07-01 DOI: 10.1186/s44342-025-00049-0 Negar Souod, Hamid Madanchi, Fariborz Bahrami, Saeed Reza Pakzad, Fereshteh Shahcheraghi, Soheila Ajdary

Gene expression network analysis identified CDK1 and KIF11 as possible key molecules in the development of colorectal cancer from normal tissues.

Pub Date : 2025-06-02 DOI: 10.1186/s44342-025-00046-3 Soo Bin Lee, Young Seon Noh, Ji-Wook Moon, Soohyun Sim, Sung Won Han, Eun Sun Kim, Ji-Yun Lee

Non-variable RNA deletion using the CRISPR-Cas9 technique demonstrated improved outcomes in human intestine single-cell RNA sequencing data, even at half sequencing depths.

Pub Date : 2025-05-20 DOI: 10.1186/s44342-025-00043-6 Dong Jun Kim, Christine Suh Yun Joh, So Young Jeong, Yong Jun Kim, Seong Joon Koh, Hyun Je Kim