Physical Activity Increases Immunity to COVID-19 Infection.

IF 0.8 4区 医学 Q4 IMMUNOLOGY
Kiran Dudhat
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引用次数: 0

Abstract

Coronavirus are truly one of the maximum critical fantastic-stranded non-segmented RNA viruses, named after the approximately 126-nm-diameter envelope around the nucleic acid-protein complicated. The virus causes significant harm to human fitness, including direct injury to the respiratory system, immune system compromise, worsening of the underlying clinical conditions, and eventually systemic failure and death. Exercise affects the immune system's antiviral mechanisms. Modest exercise, done before or after infection, improves morbidity and mortality to the contamination, according to animal investigations using influenza and simplex virus in the respiratory tract. Moreover, preclinical research has demonstrated that overtraining has a negative impact on the body's response to viral infections. Follow-up research has shed some light on the mechanisms underlying these discoveries. Through the activation of muscle protein synthesis, physical activity (PA) and exercise are essential for maintaining muscle mass. On the other hand, a lack of muscle contractile activity throughout the country of no exercise, particularly in elderly people, is a major contributor to anabolic rigidity and muscle atrophy.

体育活动增强对新冠肺炎感染的免疫力。
冠状病毒确实是最关键的奇妙链非分段RNA病毒之一,以复杂核酸蛋白周围直径约126纳米的包膜命名。该病毒对人体健康造成重大危害,包括对呼吸系统的直接伤害、免疫系统受损、潜在临床状况恶化,最终导致系统衰竭和死亡。运动会影响免疫系统的抗病毒机制。根据使用呼吸道流感和单纯性病毒进行的动物调查,在感染前或感染后进行适度的运动可以提高感染的发病率和死亡率。此外,临床前研究表明,过度训练对身体对病毒感染的反应有负面影响。后续研究揭示了这些发现背后的机制。通过激活肌肉蛋白质合成,体育活动(PA)和锻炼对保持肌肉质量至关重要。另一方面,在全国范围内缺乏肌肉收缩活动,尤其是老年人,是导致合成代谢强直和肌肉萎缩的主要原因。
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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
14
审稿时长
>12 weeks
期刊介绍: Immunology covers a broad spectrum of investigations at the genes, molecular, cellular, organ and system levels to reveal defense mechanisms against pathogens as well as protection against tumors and autoimmune diseases. The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in medical sciences. Critical ReviewsTM in Immunology (CRI) seeks to present a balanced overview of contemporary adaptive and innate immune responses related to autoimmunity, tumor, microbe, transplantation, neuroimmunology, immune regulation and immunotherapy from basic to translational aspects in health and disease. The articles that appear in CRI are mostly obtained by invitations to active investigators. But the journal will also consider proposals from the scientific community. Interested investigators should send their inquiries to the editor before submitting a manuscript.
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