The usefulness of the apparent diffusion coefficient value in diagnosing acute spinal cord ischemia.

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Nagoya Journal of Medical Science Pub Date : 2023-08-01 DOI:10.18999/nagjms.85.3.612

Norikazu Koori, Joe Senda, Takehiro Naito

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Abstract

The purpose of our study was to assess the usefulness of the apparent diffusion coefficient (ADC) value in differentiating between a normal spinal cord and a spinal cord with acute ischemia. Control group of 113 and 8 acute spinal cord ischemia patients were enrolled in this study. The ADC values were measured when diffusion-weighted imaging was first performed after the onset of acute spinal cord ischemia. The mean ADC value each of the control group and acute spinal cord ischemia patients was 0.99 ± 0.19 × 10^-3 mm²/s and 0.70 ± 0.15 × 10^-3 mm²/s. The mean ADC value in patients with acute spinal cord ischemia was significantly lower than that in patients with a normal spinal cord (P < 0.01). We found the cutoff ADC value (0.86 × 10^-3 mm²/s) to be a useful indicator of acute spinal cord ischemia (sensitivity = 100.0%, specificity = 71.7%, AUC = 0.92). In conclusions, it is suggested that the ADC value may be useful in the diagnosis of acute spinal cord ischemia.

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表观扩散系数值在诊断急性脊髓缺血中的作用。

我们研究的目的是评估表观扩散系数（ADC）值在区分正常脊髓和急性缺血脊髓方面的有用性。对照组包括113名和8名急性脊髓缺血患者。ADC值是在急性脊髓缺血发作后首次进行扩散加权成像时测量的。对照组和急性脊髓缺血患者的平均ADC值分别为0.99±0.19×10-3 mm2/s和0.70±0.15×10-3 mm2/s。急性脊髓缺血患者的平均ADC值显著低于正常脊髓患者（P<0.01）。我们发现截断ADC值（0.86×10-3 mm2/s）是急性脊髓缺血的有用指标（敏感性=1000%，特异性=71.7%，AUC=0.92），提示ADC值可用于急性脊髓缺血的诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nagoya Journal of Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal publishes original papers in the areas of medical science and its related fields. Reviews, symposium reports, short communications, notes, case reports, hypothesis papers, medical image at a glance, video and announcements are also accepted. Manuscripts should be in English. It is recommended that an English check of the manuscript by a competent and knowledgeable native speaker be completed before submission.