Incidence of Dysmagnesemia among Medically Hospitalized Patients and Associated Clinical Characteristics: A Prospective Cohort Study.

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

International Journal of Endocrinology Pub Date : 2023-10-04 eCollection Date: 2023-01-01 DOI:10.1155/2023/6650620

Zahra Al Shukri, Juhaina Salim Al-Maqbali, Abdullah M Al Alawi, Nafila Al Riyami, Sulaiman Al Riyami, Hiba Al Alawi, Qatiba Al Farai, Henrik Falhammar

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引用次数: 0

Abstract

Background: Magnesium (Mg) disorders are common among hospitalized patients and are linked to poor health outcomes. We aimed to determine the incidence of dysmagnesemia among medically hospitalized patients and to identify factors that are associated with dysmagnesemia.

Methods: A prospective cohort study was conducted at Sultan Qaboos University Hospital (SQUH) from April 1st, 2022, to October 31st, 2022, and involved hospitalized adult patients (≥18 years) under the care of the general internal medicine unit. The patients' serum total magnesium (Mg) concentrations were categorized as hypomagnesemia (≤0.69 mmol/L), hypermagnesemia (≥1.01 mmol/L), or dysmagnesemia, which encompassed either hypomagnesemia or hypermagnesemia.

Results: Of the 304 patients evaluated, dysmagnesemia was observed in 22.0%, which comprised of 17.4% with hypomagnesemia and 4.6% with hypermagnesemia. Statistically significant associations were identified between hypermagnesemia and chronic kidney disease (CKD) (p = 0.05) and elevated creatinine levels (p < 0.01) and lower estimated glomerular filtration rate (eGFR) (p < 0.01). Hypomagnesemia was linked to lower ionized calcium (p = 0.03) and admission due to infectious diseases (p = 0.02). However, ordered regression analysis did not find any significant associations with the different magnesium groups.

Conclusion: Dysmagnesemia was prevalent among hospitalized patients and was associated with different factors; however, ordered regression analysis did not find any association with the different magnesium group, probably due to the limited number of included individuals.

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住院患者中镁营养不良的发生率及相关临床特征：一项前瞻性队列研究。

背景：镁（Mg）障碍在住院患者中很常见，并与不良的健康状况有关。我们的目的是确定医学住院患者中痛经的发生率，并确定与痛经相关的因素。方法：一项前瞻性队列研究于2022年4月1日至2022年10月31日在苏丹卡布斯大学医院进行，涉及住院的成年患者（≥18 年），由普通内科护理。患者的血清总镁（Mg）浓度被归类为低镁血症（≤0.69 mmol/L）、高镁血症（≥1.01 mmol/L），或包括低镁血症或高镁血症的味觉障碍。结果：在评估的304例患者中，有22.0%的患者出现味觉障碍，其中17.4%为低镁血症，4.6%为高镁血症。高镁血症和慢性肾脏疾病（CKD）之间存在统计学上显著的相关性（p = 0.05）和肌酐水平升高（p p p = 0.03）和因传染病入院（p = 0.02）。然而，有序回归分析没有发现与不同镁组有任何显著关联。结论：镁营养不良在住院患者中普遍存在，并与不同因素有关；然而，有序回归分析没有发现与不同镁组有任何关联，这可能是由于纳入的个体数量有限。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Endocrinology ENDOCRINOLOGY & METABOLISM-

CiteScore

5.20

自引率

0.00%

发文量

147

审稿时长

1 months

期刊介绍： International Journal of Endocrinology is a peer-reviewed, Open Access journal that provides a forum for scientists and clinicians working in basic and translational research. The journal publishes original research articles, review articles, and clinical studies that provide insights into the endocrine system and its associated diseases at a genomic, molecular, biochemical and cellular level.