The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study.

IF 0.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Asian Biomedicine Pub Date : 2023-10-09 eCollection Date: 2023-06-01 DOI:10.2478/abm-2023-0054

Chunchuree Kongmeesuk Kaneko, Katsunori Kaneko, Vitoon Jularattanaporn, Thamthiwat Nararatwanchai

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引用次数: 0

Abstract

Background: Inflammation may be associated with macular pigment optical density (MPOD) degradation.

Objectives: The relationship between inflammation and MPOD is evaluated using inflammatory biomarkers, including high sensitivity C-reactive protein (hsCRP), lipid level and ratio, waist circumference (WC), and body mass index (BMI).

Method: In this cross-sectional design, 62 hypertensive patients were recruited between January 6 and January 8, 2022, at a primary care unit. The MPOD was measured using the Macular pigment screener II. Blood tests for hsCRP, lipid profile, WC measurement, BMI calculation, and completing a questionnaire were conducted, and statistical analysis was done by using Microsoft Excel 2019 and Stata version 16.1. Spearman's rank correlation test was used to evaluate correlations. Multivariate analysis for adjusting confounders was done by logistic regression.

Result: There was a significant negative correlation between hsCRP >3 and MPOD (r = -0.26, P = 0.04).

Conclusion: Inflammation was linked to MPOD. Anti-inflammatory agents may be beneficial in preventing MPOD degradation.

查看原文本刊更多论文

炎症生物标志物与高血压患者黄斑色素光密度之间的关系：一项横断面研究。

背景：炎症可能与黄斑色素光密度（MPOD）降解有关。目的：使用炎症生物标志物评估炎症与MPOD之间的关系，包括高敏C反应蛋白（hsCRP）、脂质水平和比率、腰围（WC）和体重指数（BMI）。MPOD是使用Macular颜料筛分器II测量的。进行了hsCRP、脂质概况、WC测量、BMI计算和填写问卷的血液测试，并使用Microsoft Excel 2019和Stata 16.1版进行了统计分析。Spearman秩相关检验用于评估相关性。通过逻辑回归进行多变量分析以调整混杂因素。结果：hsCRP>3与MPOD呈显著负相关（r=-0.26，P=0.04）。抗炎剂可能有利于防止MPOD降解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Biomedicine 医学-医学：研究与实验

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Asian Biomedicine: Research, Reviews and News (ISSN 1905-7415 print; 1875-855X online) is published in one volume (of 6 bimonthly issues) a year since 2007. [...]Asian Biomedicine is an international, general medical and biomedical journal that aims to publish original peer-reviewed contributions dealing with various topics in the biomedical and health sciences from basic experimental to clinical aspects. The work and authorship must be strongly affiliated with a country in Asia, or with specific importance and relevance to the Asian region. The Journal will publish reviews, original experimental studies, observational studies, technical and clinical (case) reports, practice guidelines, historical perspectives of Asian biomedicine, clinicopathological conferences, and commentaries Asian biomedicine is intended for a broad and international audience, primarily those in the health professions including researchers, physician practitioners, basic medical scientists, dentists, educators, administrators, those in the assistive professions, such as nurses, and the many types of allied health professionals in research and health care delivery systems including those in training.