Percutaneous Coronary Interventions in Women.

IF 5.7 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Atherosclerosis Reports Pub Date : 2023-11-01 Epub Date: 2023-10-10 DOI:10.1007/s11883-023-01150-x

Golsa Joodi, Sristi Palimar, Marcella Calfon Press

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Abstract

Purposeof review: Cardiovascular disease is the leading cause of morbidity and mortality among women globally. Numerous studies show ongoing disparities in diagnosis, management, and outcomes of ischemic heart disease in women compared to men. We aim to review the factors contributing to sex-based differential outcomes of percutaneous coronary interventions in women.

Recent findings: Hormonal influence on coronary arteries and progression of atherosclerosis in women results in distinct coronary plaque characteristics and unique pathological process such as spontaneous coronary artery dissection and myocardial infarction with non-obstructive coronary arteries. During the presentation of acute coronary syndromes, women are older and have higher burden of comorbidities, with higher short- and long-term mortality. Awareness of differences in vascular biology and unique risk factors for cardiovascular disease in women is essential for sustained improvement in cardiovascular mortality. Better representation of women in trials is crucial to address the gaps in knowledge and allow for individualized treatment approaches in women.

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女性经皮冠状动脉介入治疗。

综述目的：心血管疾病是全球女性发病率和死亡率的主要原因。大量研究表明，与男性相比，女性在缺血性心脏病的诊断、管理和结果方面存在持续的差异。我们的目的是回顾导致女性经皮冠状动脉介入治疗基于性别的差异结果的因素。最近的研究结果：激素对冠状动脉的影响和女性动脉粥样硬化的进展导致了独特的冠状动脉斑块特征和独特的病理过程，如自发性冠状动脉夹层和非阻塞性冠状动脉心肌梗死。在急性冠状动脉综合征期间，女性年龄较大，合并症负担较高，短期和长期死亡率较高。了解女性心血管疾病的血管生物学差异和独特风险因素对于持续改善心血管死亡率至关重要。提高妇女在试验中的代表性对于解决知识差距和为妇女提供个性化治疗方法至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Atherosclerosis Reports 医学-

CiteScore

9.00

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of this journal is to systematically provide expert views on current basic science and clinical advances in the field of atherosclerosis and highlight the most important developments likely to transform the field of cardiovascular prevention, diagnosis, and treatment. We accomplish this aim by appointing major authorities to serve as Section Editors who select leading experts from around the world to provide definitive reviews on key topics and papers published in the past year. We also provide supplementary reviews and commentaries from well-known figures in the field. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.