Bioarchaeological study of ancient Teotihuacans based on complete mitochondrial genome sequences and diet isotopes.

IF 1.2 4区医学 Q2 ANTHROPOLOGY

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2023-10-09 DOI:10.1080/03014460.2023.2261844

Fuzuki Mizuno, Fuyuki Tokanai, Masahiko Kumagai, Koji Ishiya, Saburo Sugiyama, Michiko Hayashi, Kunihiko Kurosaki, Shintaroh Ueda

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引用次数: 0

Abstract

Background: The Teotihuacan civilisation was the largest one in ancient Mesoamerica. The Teotihuacan city was born in the north-eastern Basin of Mexico around the second century BC, reached its peak in the fourth century AD, and had cultural influence throughout Mesoamerica. At its peak, the size of the city reached more than 20 km², and the total population is estimated to have increased from 100,000 to 200,000. However, knowledge of the genetic background of the Teotihuacan people is still limited.

Aim: We aimed to determine the mitogenome sequences of the Teotihuacan human remains and compare the ancient and present Mesoamericans. In addition, we aimed to identify the food habits of ancient Teotihuacans.

Subjects and methods: We determined the mitogenome sequences of human remains dated to 250-636 cal AD using target enrichment-coupled next generation sequencing. We also performed stable isotope analysis.

Results: We successfully obtained nearly full-length sequences newly unearthed from a civilian dwelling in the Teotihuacan site. Teotihuacan mitochondrial DNA was classified into the haplogroups in present and ancient Mesoamericans. In addition, Teotihuacan individuals had a diet dependent on C4 plants such as maize.

Conclusion: Genetic diversity varied among the Teotihuacans.

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基于线粒体全基因组序列和饮食同位素的古代特奥替华Can的生物考古学研究。

背景：特奥蒂瓦坎文明是古代中美洲最大的文明。特奥蒂瓦坎市大约在公元前2世纪诞生于墨西哥东北部盆地，在公元4世纪达到顶峰，并在整个中美洲产生了文化影响。在鼎盛时期，这座城市的面积达到了20多平方公里，总人口估计已从10万增加到20万。然而，对特奥蒂瓦坎人的遗传背景的了解仍然有限。目的：我们旨在确定特奥蒂瓦坎人类遗骸的有丝分裂基因组序列，并对古代和现代中美洲人进行比较。此外，我们还旨在确定古代特奥蒂瓦坎人的饮食习惯。研究对象和方法：我们确定了250-636年人类遗骸的有丝分裂基因组序列使用靶富集偶联的下一代测序的cal AD。我们还进行了稳定同位素分析。结果：我们成功地获得了特奥蒂瓦坎遗址一处民宅新出土的近全长序列。Teotihuacan线粒体DNA在现今和古代中美洲被分为单倍群。此外，Teotihuacan个体的饮食依赖于C4植物，如玉米。结论：特奥替华Can的遗传多样性不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Human Biology 生物-公共卫生、环境卫生与职业卫生

CiteScore

3.40

自引率

5.90%

发文量

审稿时长

1 months

期刊介绍： Annals of Human Biology is an international, peer-reviewed journal published six times a year in electronic format. The journal reports investigations on the nature, development and causes of human variation, embracing the disciplines of human growth and development, human genetics, physical and biological anthropology, demography, environmental physiology, ecology, epidemiology and global health and ageing research.