Correlation between Coronary Artery Disease and Non-Alcoholic Fatty Liver Disease Using Computed Tomography Coronary Calcium Scans.

Current health sciences journal Pub Date : 2023-04-01 Epub Date: 2023-06-30 DOI:10.12865/CHSJ.49.02.244
Dragoș Constantin Cucoranu, Marian Pop, Raluca Niculescu, Irina-Bianca Kosovski, Radu-Ovidiu Toganel, Razvan-Andrei Licu, Anca Bacârea
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Abstract

Introduction: Concerns about how non-alcoholic fatty liver disease (NAFLD) might contribute to the development of cardiovascular disease (CVD) have grown as the importance of NAFLD and its relationship to the metabolic syndrome has grown. The purpose of this cross-sectional retrospective is to investigate potential correlations between hepatic steatosis in liver segments seen when measuring calcium score and the presence of atherosclerotic CAD (coronary artery disease).

Methods: Two hundred patients (mean age, 57 years±10) who underwent coronary cardiac computed tomography (CT) scans were included. CT scans were analysed to assess the attenuation of liver parenchyma and the coronary artery calcification (CAC).

Results: Age, gender, body mass index (BMI) and CAC score were significantly associated with hepatic steatosis. Among all patients, CAC score (r=-0.31, p<0.0001), and BMI (r=-0.40, p<0.0001) had a moderate negative correlation with the values of liver attenuation. BMI (OR: 1.109, p=0.001), CAC score (OR: 1.629, p<0.001), and age (OR: 1.050, p<0.001) were found to be independent predictors of hepatic steatosis through logistic regression.

Conclusions: A statistically significant correlation between CAC score and the presence of NAFLD as evaluated by non-contrast-enhanced CT was demonstrated. BMI, CAC score, and age were identified as independent predictors of hepatic steatosis.

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冠状动脉疾病与非酒精性脂肪肝的相关性冠状动脉钙扫描。
引言:随着非酒精性脂肪肝的重要性及其与代谢综合征的关系的增加,人们越来越担心非酒精性脂性肝病(NAFLD)可能会导致心血管疾病(CVD)的发展。本横断面回顾性研究的目的是研究在测量钙评分时发现的肝节段肝脂肪变性与动脉粥样硬化性CAD(冠状动脉疾病)之间的潜在相关性。方法:包括200名接受冠状动脉计算机断层扫描(CT)的患者(平均年龄,57岁±10岁)。结果:年龄、性别、体重指数(BMI)和冠状动脉钙化(CAC)评分与肝脂肪变性显著相关。在所有患者中,CAC评分(r=-0.31,P结论:非造影增强CT评估的CAC评分与NAFLD的存在之间存在统计学显著相关性。BMI、CAC评分和年龄被确定为肝脂肪变性的独立预测因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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