From Its Nature to Its Function: Marine-Collagen-Based-Biomaterials for Hard Tissue Applications.

IF 5.1 2区 医学 Q2 CELL & TISSUE ENGINEERING
Tissue Engineering. Part B, Reviews Pub Date : 2024-06-01 Epub Date: 2023-12-07 DOI:10.1089/ten.TEB.2023.0077
Gabriela S Diogo, Rogério P Pirraco, Rui L Reis, Tiago H Silva
{"title":"From Its Nature to Its Function: Marine-Collagen-Based-Biomaterials for Hard Tissue Applications.","authors":"Gabriela S Diogo, Rogério P Pirraco, Rui L Reis, Tiago H Silva","doi":"10.1089/ten.TEB.2023.0077","DOIUrl":null,"url":null,"abstract":"<p><p>Impact statement This review discusses the research done using marine collagens (MCs) on biomaterials for bone, cartilage, and osteochondral tissue regenerative applications with the underlying technologies that enable their development, and explains the methodologies used to characterize MCs highlighting their importance, namely regarding the performance of derived biomaterials, and the inherent properties of such collagens. In the second part, the applicability of MCs as biomaterials for hard tissue applications was studied, focusing on the mostly applied fabrication techniques. In conclusion, this review describes the major challenges to be overcome and the forecast for the upcoming years concerning the use of MCs.</p>","PeriodicalId":23134,"journal":{"name":"Tissue Engineering. Part B, Reviews","volume":null,"pages":null},"PeriodicalIF":5.1000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tissue Engineering. Part B, Reviews","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/ten.TEB.2023.0077","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/12/7 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0

Abstract

Impact statement This review discusses the research done using marine collagens (MCs) on biomaterials for bone, cartilage, and osteochondral tissue regenerative applications with the underlying technologies that enable their development, and explains the methodologies used to characterize MCs highlighting their importance, namely regarding the performance of derived biomaterials, and the inherent properties of such collagens. In the second part, the applicability of MCs as biomaterials for hard tissue applications was studied, focusing on the mostly applied fabrication techniques. In conclusion, this review describes the major challenges to be overcome and the forecast for the upcoming years concerning the use of MCs.

从性质到功能:用于硬组织应用的海洋胶原蛋白生物材料。
对基于胶原蛋白的治疗应用的快速增长的需求需要大量的胶原蛋白储备。商业胶原蛋白主要局限于哺乳动物来源,它们担心人畜共患疾病的转移,此外,陆地动物的过度开发问题,即使如此,也无法满足新月形对胶原蛋白的需求。从海洋生物中提取胶原蛋白,包括脊椎动物和无脊椎动物的废物,既有经济效益,也有环境效益。海洋胶原蛋白易于提取,具有良好的生物相容性和良好的吸收特性,对患者的人畜共患和免疫风险较低,宗教和监管限制较少。本综述讨论了使用海洋胶原蛋白在骨、软骨和骨软骨组织再生应用的生物材料上进行的研究,以及使其发展成为可能的潜在技术。加工海洋胶原蛋白的主要挑战与特定特征有关,如低变性温度和弱机械性能,也得到了解决。传统上,共混物和物理或化学交联处理与传统加工方法的结合仍然用于制备海洋胶原蛋白生物材料。然而,海洋胶原蛋白在医疗保健相关领域,特别是在治疗肌肉骨骼缺陷方面的作用越来越大,这促使科学界探索先进技术,设计和开发安全但功能性强的材料,以更好地满足组织的功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Tissue Engineering. Part B, Reviews
Tissue Engineering. Part B, Reviews Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
12.80
自引率
1.60%
发文量
150
期刊介绍: Tissue Engineering Reviews (Part B) meets the urgent need for high-quality review articles by presenting critical literature overviews and systematic summaries of research within the field to assess the current standing and future directions within relevant areas and technologies. Part B publishes bi-monthly.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信