Phages for treatment of Salmonella spp infection.

3区 生物学 Q2 Biochemistry, Genetics and Molecular Biology
V Baskaran, L Karthik
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引用次数: 0

Abstract

Salmonella, is one of the bacterial genera having more than 2500 serogroups is one of the most prominent food borne pathogen that is capable of causing disease out breaks among humans and animals. Recent reports clearly shows that this pathogen is evolved and it developed drug resistant towards most of the commercially available antibiotics. In order to overcome this emerging resistance, Bacteriophage therapy is one of the alternative solutions. It is more pathogen specific, high potency, and thereby highly safe for consumption. This chapter discuss about Rapid screening and Detection Methods Associated with Bacteriophage for Salmonella, commercially available phage products and regulatory status, Salmonella endolysins and future prospects of phage therapy.

用于治疗沙门氏菌感染的噬菌体。
沙门氏菌是拥有2500多个血清群的细菌属之一,是最突出的食源性病原体之一,能够在人类和动物中引起疾病爆发。最近的报告清楚地表明,这种病原体是进化而来的,它对大多数商业上可用的抗生素产生了耐药性。为了克服这种新出现的耐药性,噬菌体疗法是替代方案之一。它更具病原体特异性,效力高,因此食用安全性高。本章讨论了与噬菌体相关的沙门氏菌的快速筛选和检测方法、市售噬菌体产品和监管现状、沙门氏菌内溶素以及噬菌体治疗的未来前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.00
自引率
0.00%
发文量
110
审稿时长
4-8 weeks
期刊介绍: Progress in Molecular Biology and Translational Science (PMBTS) provides in-depth reviews on topics of exceptional scientific importance. If today you read an Article or Letter in Nature or a Research Article or Report in Science reporting findings of exceptional importance, you likely will find comprehensive coverage of that research area in a future PMBTS volume.
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