Application of Complete Decongestive Therapy in Patients with Secondary Bilateral Lower Limb Lymphedema after Comprehensive Treatment of Gynecological Malignant Tumor.

IF 1.6 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Lymphatic research and biology Pub Date : 2024-02-01 Epub Date: 2023-10-03 DOI:10.1089/lrb.2023.0029

Yuanli Zeng, Gaoming Liu, Zheng Peng, Jin Hu, Anhui Zhang

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引用次数: 0

Abstract

Objective: The purpose of this study is to investigate the effect of complete decongestive therapy (CDT), based on fluoroscopy-guided manual lymph drainage (FG-MLD), combined with intermittent pneumatic compression (IPC) on patients with secondary bilateral lower limb lymphedema after comprehensive treatment for gynecological malignant tumors. Methods: After comprehensive treatment for gynecological malignant tumors, 18 patients suffering from bilateral lower limb lymphedema were evaluated and treated by specialist nurses (with the qualification of lymphedema therapists). The treatment course included manual drainage, IPC, bandaging, functional exercise, and skincare etc., which are performed once a day for a total of 18 times. Results: After performing the treatment 18 times, a significant reduction is observed in the patient's bilateral lower limb circumference, extracellular water (ECW) content, and lower limb segment ECW ratio. Moreover, the 50-kHz bioelectrical impedance and quality of life (QoL) scores are found to be significantly higher than before treatment (all p < 0.05). Subjective symptoms also improve significantly (p < 0.05), except for local swelling (p = 0.289 > 0.05). Conclusions: CDT based on FG-MLD, combined with IPC, effectively relieves secondary bilateral lower limb lymphedema after comprehensive treatment of gynecological malignant tumors. It also improves subjective symptoms and patients' QoL, thus deserving clinical reference and promotion.

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完全消融术在妇科恶性肿瘤综合治疗后继发性双侧下肢淋巴水肿中的应用。

目的：探讨在透视引导下手动淋巴引流（FG-MLD）的基础上，采用完全缓解充血疗法（CDT）配合间歇气压按压（IPC）治疗妇科恶性肿瘤综合治疗后继发性双侧下肢淋巴水肿的疗效。方法：对18例双侧下肢淋巴水肿患者进行妇科恶性肿瘤综合治疗后，由具有淋巴水肿治疗师资格的专科护士进行评估和治疗。疗程包括手动引流、IPC、包扎、功能锻炼、护肤等，每天1次，共18次。结果：在进行18次治疗后，观察到患者的双侧下肢周长、细胞外水（ECW）含量和下肢节段ECW比率显著降低。此外，50kHz生物电阻抗和生活质量（QoL）评分显著高于治疗前（均p p p = 0.289 > 结论：以FG-MLD为基础的CDT联合IPC能有效缓解妇科恶性肿瘤综合治疗后继发性双侧下肢淋巴水肿。它还改善了患者的主观症状和生活质量，值得临床借鉴和推广。

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来源期刊

Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine

CiteScore

3.10

自引率

7.10%

发文量

审稿时长

>12 weeks

期刊介绍： Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease