Determination of ethyl glucuronide in hair and self-reported alcohol consumption in university students.

IF 1.5 4区 医学 Q2 MEDICINE, LEGAL
Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-10-05 DOI:10.1007/s12024-023-00727-x
Jennifer P Pascali, Arianna Giorgetti, Guido Pelletti, Luca Morini, Susan Mohamed, Marta Barbaresi, Rossana Cecchi, Susi Pelotti, Paolo Fais
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Abstract

Young individuals constitute an intriguing population, as their drinking habits are notably shaped by their perception of their peers' alcohol consumption. Nonetheless, excessive alcohol intake can have detrimental effects on academic performance, interpersonal relationships, and the risk and severity of accidents. This study reported the first data involving students enrolled from three universities on a voluntary basis for alcohol consumption evaluation. Alcohol consumption was assessed through questionnaires and EtG quantification in hair (hEtG) carried out by liquid chromatography-mass spectrometry (LC-MS/MS) analysis after a solid-phase extraction (SPE) purification step. The results of our study demonstrated that 77.1% of samples tested negative for hEtG or displayed hEtG ≤ 5 pg/mg. Particularly, the student population was not characterized by samples with hEtG indicative of chronic excessive consumption (hEtG ≥ 30 pg/mg). No significant association was identified between biological sex, among the degree course/the year attended, nor in relation to BMI or smoking/coffee consumption. Among the obtained results, it was worth noting that the comparison of self-reporting abstinence from tobacco and coffee accounted for 65.3% and 16.7%, respectively, while only 2.8% of the total declared abstinence from alcohol. The current study has uncovered a significant level of interest among students in this analysis and its interpretation. This suggests that implementing public health promotion activities within a university setting could be beneficial.

Abstract Image

头发中乙基葡糖苷酸的测定和大学生自我报告的饮酒量。
年轻人是一个有趣的群体,因为他们的饮酒习惯明显受到同龄人饮酒情况的影响。尽管如此,过量饮酒会对学习成绩、人际关系以及事故的风险和严重程度产生不利影响。这项研究报告了第一批涉及三所大学自愿入学的学生的酒精消费评估数据。通过问卷调查和在固相萃取(SPE)纯化步骤后通过液相色谱-质谱(LC-MS/MS)分析进行的头发中EtG定量(hEtG)来评估酒精消耗。我们的研究结果表明,77.1%的样本检测出hEtG阴性或显示hEtG ≤ 5 pg/mg。特别是,学生群体没有以hEtG样本为特征,该样本表明长期过量消费(hEtG ≥ 30pg/mg)。在生物性别、学位课程/就读年份之间,以及与BMI或吸烟/咖啡消费之间,均未发现显著关联。在获得的结果中,值得注意的是,自我报告戒烟和咖啡的比较分别占65.3%和16.7%,而只有2.8%的人宣布戒酒。目前的研究发现,学生们对这一分析及其解释有很大的兴趣。这表明,在大学环境中开展公共卫生促进活动可能是有益的。
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来源期刊
Forensic Science, Medicine and Pathology
Forensic Science, Medicine and Pathology MEDICINE, LEGAL-PATHOLOGY
CiteScore
3.90
自引率
5.60%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.
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