Thaís de Oliveira Fernandes, Patrícia Arriaga Carvalho, Fernanda Volpe de Abreu, Christian Kirschneck, Erika Calvano Küchler, Leonardo Santos Antunes, Lívia Azeredo Alves Antunes
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引用次数: 0
Abstract
An increasing number of systematic reviews (SR) has investigated the association between dental caries and nutritional status in children and adolescents, thus requiring an overview to compile the information in a single piece of evidence. Therefore, this study aimed to evaluate and summarize evidence from published SR on the association between dental caries and nutritional status in children and adolescents. A wide search was conducted on May 29, 2023, in six databases (Medline via PubMed, Scopus, Web of Science, Cochrane library, Embase, and the Virtual Health Library - VHL). An additional search was performed in the gray literature (Open grey and Google Scholar), SR registration databases, and the list of references of the included SR. Our inclusion criteria were based on acronym PECOS. Overall, two reviewers independently extracted the data, evaluated the risk of bias (ROBIS), and assessed the quality of the chosen studies (AMSTAR-2). Data from the included meta-analysis were summarized and certainty of evidence using the GRADE approach was performed. After removing duplicates and applying our eligibility criteria, 19 SR from 2006-2022 were included. We found that 17 SR showed high risk of bias and critically low methodological quality. We observed an association between dental caries experiences and nutritional status since seven SR found an association between obesity/overweight and dental caries; one, an association between underweight and dental caries; and eleven, no associations. The meta-analysis showed divergent results according to the study designs, used indices, and participants' age group, and were scored as having a very low certainty of evidence. Therefore, based on the high risk of bias, low methodological quality, and very low certainty of evidence of the chosen SR, most studies found no association between children and adolescents' nutritional status and dental caries experience.
越来越多的系统综述(SR)调查了儿童和青少年龋齿与营养状况之间的关系,因此需要对信息进行综述,以将其汇编成一份单一的证据。因此,本研究旨在评估和总结已发表的SR中关于儿童和青少年龋齿与营养状况之间关系的证据。2023年5月29日,在六个数据库(Medline via PubMed、Scopus、Web of Science、Cochrane图书馆、Embase和虚拟健康图书馆-VHL)中进行了广泛搜索。在灰色文献(Open grey和Google Scholar)、SR注册数据库和纳入SR的参考文献列表中进行了额外搜索。我们的纳入标准基于首字母缩写PECOS。总体而言,两名评审员独立提取数据,评估偏倚风险(ROBIS),并评估所选研究的质量(AMSTAR-2)。对纳入的荟萃分析的数据进行了总结,并使用GRADE方法进行了证据的确定性。在删除重复项并应用我们的资格标准后,纳入了2006-2022年的19项SR。我们发现17例SR显示出较高的偏倚风险和极低的方法学质量。我们观察到龋齿经历与营养状况之间存在关联,因为7名SR发现肥胖/超重与龋齿之间存在关联;一是体重不足与龋齿之间的关联;十一个,没有关联。根据研究设计、使用的指标和参与者的年龄组,荟萃分析显示出不同的结果,并且被认为证据的确定性非常低。因此,基于所选SR的高偏倚风险、低方法质量和极低的证据确定性,大多数研究发现儿童和青少年的营养状况与龋齿经历之间没有关联。
期刊介绍:
The Journal of Applied Oral Science is committed in publishing the scientific and technologic advances achieved by the dental community, according to the quality indicators and peer reviewed material, with the objective of assuring its acceptability at the local, regional, national and international levels. The primary goal of The Journal of Applied Oral Science is to publish the outcomes of original investigations as well as invited case reports and invited reviews in the field of Dentistry and related areas.