Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties

JCPP advances Pub Date : 2023-03-30 DOI:10.1002/jcv2.12154

Celestine Lockhart, Joanna Bright, Yasmin Ahmadzadeh, Gerome Breen, Shannon Bristow, Andy Boyd, Johnny Downs, Matthew Hotopf, Elisavet Palaiologou, Kaili Rimfeld, Jessye Maxwell, Margherita Malanchini, Tom A. McAdams, Andrew McMillan, Robert Plomin, Thalia C. Eley

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引用次数: 4

Abstract

The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

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双胞胎早期发展研究（TEDS）：一项对20多岁中期心理健康结果的基因敏感调查。

双胞胎早期发育研究（TEDS）是对1994-1996年出生于英格兰和威尔士的双胞胎进行的一项纵向研究。在最初同意参与的13759个家庭中，仍有超过10000个家庭参与了这项研究。TEDS目前关注的焦点是20多岁中期的心理健康。TEDS利用超过25年的基因敏感数据，在探索成年早期常见心理健康障碍的纵向基因和环境影响方面处于独特地位。本文概述了最近支持这项工作的数据收集工作，包括26岁时的全人群心理健康评估和多阶段新冠肺炎研究。它还将提供数据链接工作和TEDS儿童项目的最新情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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JCPP advances

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审稿时长

13 weeks