AoA-L2 and Usage-L2 modulate the functional neuroplasticity of the subcortex

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2023-10-01 DOI:10.1016/j.bandl.2023.105323

Xiaojin Liu , Zhenni Gao , Wen Liu , Xintong He , Naiyi Wang

{"title":"AoA-L2 and Usage-L2 modulate the functional neuroplasticity of the subcortex","authors":"Xiaojin Liu , Zhenni Gao , Wen Liu , Xintong He , Naiyi Wang","doi":"10.1016/j.bandl.2023.105323","DOIUrl":null,"url":null,"abstract":"<div><p>Previous studies revealed structural differences in subcortical regions between monolinguals and bilinguals; however, whether the functional neuroplasticity of the subcortex is modulated by different bilingual experiences remains unclear. Here, we examined the effect of age of second language acquisition (AoA-L2) and usage of L2 (Usage-L2) on subcorto-cortical and intra-subcortical functional connectivity (FC) in bilinguals by using resting-state fMRI data. The relations between brain measurements and bilingual experiences were revealed by using multiple regression analysis. We found that increased AoA-L2 was mainly related to decreased subcortical FC involving the anterior thalamus, basal ganglia, and hippocampus. Increased Usage-L2 at home was mainly associated with decreased subcortical FC of the amygdala, globus pallidus, hippocampus, and nucleus accumbens. The FC of these subcortical regions displayed a positive relation with Usage-L2 in social settings. These findings reveal that bilingual experiences modulate the functional neuroplasticity of the subcortex in different ways.</p></div>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0093934X23001025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}

引用次数: 0

Abstract

Previous studies revealed structural differences in subcortical regions between monolinguals and bilinguals; however, whether the functional neuroplasticity of the subcortex is modulated by different bilingual experiences remains unclear. Here, we examined the effect of age of second language acquisition (AoA-L2) and usage of L2 (Usage-L2) on subcorto-cortical and intra-subcortical functional connectivity (FC) in bilinguals by using resting-state fMRI data. The relations between brain measurements and bilingual experiences were revealed by using multiple regression analysis. We found that increased AoA-L2 was mainly related to decreased subcortical FC involving the anterior thalamus, basal ganglia, and hippocampus. Increased Usage-L2 at home was mainly associated with decreased subcortical FC of the amygdala, globus pallidus, hippocampus, and nucleus accumbens. The FC of these subcortical regions displayed a positive relation with Usage-L2 in social settings. These findings reveal that bilingual experiences modulate the functional neuroplasticity of the subcortex in different ways.

查看原文本刊更多论文

AoA-L2和Usage-L2调节皮质下的功能性神经可塑性。

先前的研究揭示了单语者和双语者皮层下区域的结构差异；然而，皮层下的功能性神经可塑性是否受到不同双语经历的调节仍不清楚。在这里，我们通过静息态fMRI数据研究了第二语言习得年龄（AoA-L2）和L2使用（usage-L2）对双语者大脑皮层下和皮层内功能连接（FC）的影响。通过多元回归分析揭示了大脑测量与双语体验之间的关系。我们发现，AoA-L2的增加主要与涉及前丘脑、基底节和海马的皮质下FC的减少有关。在家中使用-L2的增加主要与杏仁核、苍白球、海马体和伏隔核的皮质下FC减少有关。这些皮层下区域的FC与社交环境中的Usage-L2呈正相关。这些发现表明，双语经历以不同的方式调节皮层下的功能性神经可塑性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464