Computed tomography perfusion software pipelines to assess parameter maps and ischemic volumes: A comparative study

IF 2.3 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Neuroimaging Pub Date : 2023-09-22 DOI:10.1111/jon.13154

Wei Lu, Feirong Yao, Congguo Yin, Shu Wan, Xin Liu, Chongxin He, Xiaochang Leng, Jens Fiehler, Adnan H. Siddiqui, Ya Peng, Jianping Xiang

引用次数: 0

Abstract

This study was dedicated to investigating the agreement of the calculated results of two CT perfusion (CTP) postprocessing software packages, including parameter maps and ischemic volume, focusing on the infarct core volume (ICV) and penumbra volume (PV).

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计算机断层扫描灌注软件管道评估参数图和缺血体积:一项比较研究

背景与目的本研究旨在探讨两种CT灌注(CTP)后处理软件包计算结果的一致性，包括参数图和缺血体积，重点是梗死核心体积(ICV)和半影体积(PV)。方法回顾性收集235例急性缺血性脑卒中患者行CTP检查。使用RAPID CTP和AccuCTP两种软件管道对所有图像进行分析，并根据两种软件包计算的ICV和PV结果进行对比分析。参数图的一致性通过均方根误差和Bland-Altman分析进行评价。采用类内相关系数(ICC)和Bland-Altman分析对ICV和PV一致性进行评价。分析了基于多阈值的ICV和PV的精度。结果AccuCTP与RAPID CTP的ICV和PV具有良好的一致性。参数图的相对差异均在10%以内，Bland-Altman分析也显示出很强的一致性。从普通最小二乘拟合结果来看，ICV和PV的拟合优度都非常高(ICV, R2= 0.975 [p<.001];PV, R2= 0.964 [p<.001])。对于ICC分析，两者的ICC得分都很高(ICV ICC 0.984, 95% CI[置信区间]0.973-0.989;Pv ICC 0.955, 95% ci 0.947-0.964)。此外，基于ICV和PV的多阈值分析也获得了可靠的分析精度。结论AccuCTP与RAPID CTP的图像分析结果吻合良好，可作为RAPID CTP软件在脑卒中临床中的替代分析工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuroimaging 医学-核医学

CiteScore

4.70

自引率

0.00%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Start reading the Journal of Neuroimaging to learn the latest neurological imaging techniques. The peer-reviewed research is written in a practical clinical context, giving you the information you need on: MRI CT Carotid Ultrasound and TCD SPECT PET Endovascular Surgical Neuroradiology Functional MRI Xenon CT and other new and upcoming neuroscientific modalities.The Journal of Neuroimaging addresses the full spectrum of human nervous system disease, including stroke, neoplasia, degenerating and demyelinating disease, epilepsy, tumors, lesions, infectious disease, cerebral vascular arterial diseases, toxic-metabolic disease, psychoses, dementias, heredo-familial disease, and trauma.Offering original research, review articles, case reports, neuroimaging CPCs, and evaluations of instruments and technology relevant to the nervous system, the Journal of Neuroimaging focuses on useful clinical developments and applications, tested techniques and interpretations, patient care, diagnostics, and therapeutics. Start reading today!