Eimeria granulosa causes spots visible through the serous membrane of small intestine in sheep

IF 1.4 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular and biochemical parasitology Pub Date : 2023-09-18 DOI:10.1016/j.molbiopara.2023.111595

Yuanyuan Chen , Jing Liu , Xiaolei Liu , Qiaocheng Chang , Xiaoxiao Ma , Qinwei Xu

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引用次数: 0

Abstract

Coccidiosis, also known as Eimeriosis, is a highly prevalent parasitic disease affecting sheep in nearly all sheep-rearing nations across the globe. Currently, there is a scarcity of literature documenting the specific lesions in sheep resulting from coccidia infection. This study aimed to investigate these characteristic lesions through necropsy, microscopic observation, and molecular biological techniques. As a result, Eimeria granulosa was identified as the causative agent, which induced distinct pathological alterations in the small intestine of lambs as observed during necropsy. Notably, E. granulosa manifested as small scattered petechiae and white spots, visible through the serous membrane of the small intestine, akin to the pathology observed in E. necatrix. Therefore, this study provides valuable insights for the accurate diagnosis of coccidiosis in sheep.

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颗粒艾美耳球虫可引起绵羊小肠浆膜可见的斑点。

球虫病，也称为艾美耳球虫病，是一种高度流行的寄生虫病，影响着全球几乎所有养羊国家的绵羊。目前，很少有文献记录绵羊因球虫感染引起的特定病变。本研究旨在通过尸检、显微镜观察和分子生物学技术来研究这些特征性病变。因此，颗粒艾美耳球虫被确定为病原体，在尸检过程中观察到，它在羔羊小肠中引起了明显的病理变化。值得注意的是，颗粒E.表现为小的分散的瘀点和白色斑点，通过小肠的浆膜可见，类似于在E.necatrix中观察到的病理学。因此，本研究为绵羊球虫病的准确诊断提供了有价值的见解。

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来源期刊

Molecular and biochemical parasitology 医学-寄生虫学

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

63 days

期刊介绍： The journal provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are: • the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances • intermediary metabolism and bioenergetics • drug target characterization and the mode of action of antiparasitic drugs • molecular and biochemical aspects of membrane structure and function • host-parasite relationships that focus on the parasite, particularly as related to specific parasite molecules. • analysis of genes and genome structure, function and expression • analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance. • parasite protein trafficking, organelle biogenesis, and cellular structure especially with reference to the roles of specific molecules • parasite programmed cell death, development, and cell division at the molecular level.