The effect of zinc oxide (ZnO) nanoparticle concentration on the adhesion of mucin and Streptococcus mutans to heat-cured acrylic resin.

IF 1.9 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Dental materials journal Pub Date : 2023-11-29 Epub Date: 2023-10-04 DOI:10.4012/dmj.2023-016

Rahmadani Puspitasari, Dyah Irnawati, Widjijono

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引用次数: 0

Abstract

Incorporating zinc oxide (ZnO) nanoparticles as antibacterial fillers in heat-cured acrylic resin could decrease mucin and Streptococcus mutans (S. mutans) adhesion, reducing the incidence of dental caries in the baseplates of orthodontic patients. Here, ZnO nanoparticles were modified using 3-(trimethoxysilyl)propyl methacrylate with various concentrations, added to acrylic resin powder, homogenized, mixed with acrylic resin liquid, and processed. The composite systems interfered well with mucin and S. mutans adhesion. The lowest mean of the amount of mucin adhered was on heat-cured acrylic resin with 7.5% ZnO nanoparticles, with a standard deviation of 18.07±0.80 mg/mL. The ZnO nanoparticles with a concentration of 7.5% showed an 87.09±0.88% S. mutans adhesion in control groups with no additives. These composite systems were proven to have better physicochemical characteristics and antibacterial abilities. Combining ZnO nanoparticles with heat-cured acrylic resin has great potential for self-cleaning baseplates of orthodontic patients in the future.

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氧化锌（ZnO）纳米粒子浓度对粘蛋白和变形链球菌与热固化丙烯酸树脂粘附的影响。

在热固化丙烯酸树脂中加入氧化锌（ZnO）纳米颗粒作为抗菌填料可以减少粘蛋白和变形链球菌（S.mutans）的粘附，降低正畸患者基板中龋齿的发生率。在此，使用不同浓度的甲基丙烯酸3-（三甲氧基甲硅烷基）丙酯对ZnO纳米粒子进行改性，将其添加到丙烯酸树脂粉末中，均匀化，与丙烯酸树脂液体混合，并进行处理。复合体系能很好地干扰粘蛋白和变形链球菌的粘附。粘蛋白粘附量的最低平均值是在含有7.5%ZnO纳米颗粒的热固化丙烯酸树脂上，标准偏差为18.07±0.80mg/mL。在不添加添加剂的对照组中，浓度为7.5%的ZnO纳米颗粒显示出87.09±0.88%的变异链球菌粘附。这些复合体系被证明具有更好的物理化学特性和抗菌能力。将ZnO纳米颗粒与热固化丙烯酸树脂相结合，在未来口腔正畸患者的自清洁基板中具有巨大的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dental materials journal 医学-材料科学：生物材料

CiteScore

4.60

自引率

4.00%

发文量

102

审稿时长

3 months

期刊介绍： Dental Materials Journal is a peer review journal published by the Japanese Society for Dental Materials and Devises aiming to introduce the progress of the basic and applied sciences in dental materials and biomaterials. The dental materials-related clinical science and instrumental technologies are also within the scope of this journal. The materials dealt include synthetic polymers, ceramics, metals and tissue-derived biomaterials. Forefront dental materials and biomaterials used in developing filed, such as tissue engineering, bioengineering and artificial intelligence, are positively considered for the review as well. Recent acceptance rate of the submitted manuscript in the journal is around 30%.