Health-related quality of life by gout severity in women and men with gout in primary care: results from a questionnaire study in Western Sweden.

IF 2.2 4区医学 Q3 RHEUMATOLOGY

Scandinavian Journal of Rheumatology Pub Date : 2023-11-01 Epub Date: 2023-11-16 DOI:10.1080/03009742.2023.2240596

A J Landgren, Lth Jacobsson, E Klingberg, R Mirzaev, M Dehlin

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引用次数: 0

Abstract

Objective: We aimed to compare health-related quality of life (HRQoL) by gout severity, overall and by sex.

Method: A questionnaire was sent to patients with gout (n = 1444) identified at 12 primary care centres in Western Sweden. The questionnaire asked about comorbidities, gout-specific aspects, and HRQoL, using the RAND 36-Item Health Survey. Responders were divided into 'mild', 'moderate', or 'severe' gout based on the number of self-reported flares (0, 1-2, ≥ 3) during the past 12 months.

Results: Out of 1444 gout patients, 784 (54.3%) responded to the questionnaire. Among the respondents, 673 [560 (83.2%) men and 113 (16.8%) women] provided answers regarding the number of gout flares in the past year. Of these, 322 (47.8%), 218 (32.4%), and 133 (19.8%) were classified as having mild, moderate, and severe gout, respectively. Allopurinol use was more frequent in those with mild disease. In more severe gout, HRQoL was reduced compared to less severe gout [severe vs mild gout, mean values for physical component summary (PCS) score 39.5 vs 43.6, p = 0.002, and mental component summary (MCS) score 46.6 vs 51.1, p < 0.001]. When excluding those with a flare in the past month, the HRQoL was still worse in severe gout (vs mild), although differences were attenuated and not statistically significant for the PCS and for women.

Conclusion: Gout severity, defined as the number of flares during the past year, was associated with significant reductions in HRQoL.

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初级保健中女性和男性痛风患者痛风严重程度与健康相关的生活质量：瑞典西部一项问卷研究的结果。

目的：我们旨在通过痛风的严重程度、总体和性别来比较健康相关的生活质量（HRQoL）。方法：向瑞典西部12个初级保健中心的痛风患者（n=1444）发送问卷。该问卷使用兰德36项健康调查询问了合并症、痛风特定方面和HRQoL。根据过去12个月内自我报告的发作次数（0、1-2、≥3），受访者被分为“轻度”、“中度”或“重度”痛风。结果：在1444名痛风患者中，784人（54.3%）对问卷做出了回应。在受访者中，673名[560名（83.2%）男性和113名（16.8%）女性]提供了关于过去一年痛风发作次数的答案。其中，322（47.8%）、218（32.4%）和133（19.8%）分别被归类为轻度、中度和重度痛风。别嘌呤醇的使用在轻度疾病患者中更为频繁。在更严重的痛风中，与不太严重的痛风相比，HRQoL降低[严重与轻度痛风，身体成分汇总（PCS）评分平均值39.5 vs 43.6，p=0.002，精神成分汇总（MCS）评分46.6 vs 51.1，p结论：痛风严重程度，定义为过去一年中发作的次数，与HRQoL显著降低有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Scandinavian Journal of Rheumatology 医学-风湿病学

CiteScore

3.70

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Scandinavian Journal of Rheumatology is the official journal of the Scandinavian Society for Rheumatology, a non-profit organization following the statutes of the Scandinavian Society for Rheumatology/Scandinavian Research Foundation. The main objective of the Foundation is to support research and promote information and knowledge about rheumatology and related fields. The annual surplus by running the Journal is awarded to young, talented, researchers within the field of rheumatology.pasting The Scandinavian Journal of Rheumatology is an international scientific journal covering clinical and experimental aspects of rheumatic diseases. The journal provides essential reading for rheumatologists as well as general practitioners, orthopaedic surgeons, radiologists, pharmacologists, pathologists and other health professionals with an interest in patients with rheumatic diseases. The journal publishes original articles as well as reviews, editorials, letters and supplements within the various fields of clinical and experimental rheumatology, including; Epidemiology Aetiology and pathogenesis Treatment and prophylaxis Laboratory aspects including genetics, biochemistry, immunology, immunopathology, microbiology, histopathology, pathophysiology and pharmacology Radiological aspects including X-ray, ultrasonography, CT, MRI and other forms of imaging.