Vascular refilling depends on the ratio of blood volume to extracellular volume in hemodialysis patients.

IF 1.4 4区 医学 Q4 ENGINEERING, BIOMEDICAL
Joachim Kron, Stefanie Broszeit, John Volkenandt, Til Leimbach, Susanne Kron
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引用次数: 0

Abstract

The ratio of blood volume to extracellular volume is approximately one to three under physiological conditions and also in stable chronic hemodialysis patients. Recently, it was found that this ratio remains unchanged during hemodialysis despite ultrafiltration. This would signify that the higher the ratio, the lower the refilling and vice versa. To test this hypothesis, treatment data of a previous study were re-analyzed. In 79 stable chronic hemodialysis patients, the refilling fraction was 0.749 ± 0.094. There was a significant negative correlation (r = -0.412; p < 0.001) between the blood volume to extracellular volume ratio and the refilling fraction. The blood volume to extracellular volume relationship seems to be a significant determinant of vascular refilling: the higher the ratio, the lower the refilling, and vice versa.

血液透析患者的血管再充盈取决于血容量与细胞外容量的比值。
在生理条件下以及在稳定的慢性血液透析患者中,血容量与细胞外容量的比率约为一比三。最近,人们发现,尽管进行了超滤,但在血液透析过程中,这一比例保持不变。这意味着比率越高,再填充越低,反之亦然。为了验证这一假设,对先前研究的治疗数据进行了重新分析。在79名稳定的慢性血液透析患者中,再充盈分数为0.749 ± 0.094 = -0.412;p
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来源期刊
International Journal of Artificial Organs
International Journal of Artificial Organs 医学-工程:生物医学
CiteScore
3.40
自引率
5.90%
发文量
92
审稿时长
3 months
期刊介绍: The International Journal of Artificial Organs (IJAO) publishes peer-reviewed research and clinical, experimental and theoretical, contributions to the field of artificial, bioartificial and tissue-engineered organs. The mission of the IJAO is to foster the development and optimization of artificial, bioartificial and tissue-engineered organs, for implantation or use in procedures, to treat functional deficits of all human tissues and organs.
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