Prediction of motor outcome based on brain perfusion single photon emission computed tomography in corona radiata infarct.

IF 1.7 4区医学 Q4 NEUROSCIENCES

International Journal of Neuroscience Pub Date : 2024-12-01 Epub Date: 2023-10-13 DOI:10.1080/00207454.2023.2269476

Eunjung Kong, Donghwi Park, Min Cheol Chang

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引用次数: 0

Abstract

Background: There is limited information on brain perfusion single-photon emission computed tomography (SPECT) findings related to motor outcomes in patients with stroke. We aimed to investigate whether brain SPECT can be used to determine motor outcomes after corona radiata infarction.

Methods: Eighty-nine patients were recruited in this study. Brain SPECT and diffusion tensor tractography (DTT) were conducted to evaluate the state of the corticospinal tract (CST) within 7-30 days of corona radiata infarct. Motor outcome was measured 6 months after infarct onset and was evaluated using the modified Brunnstrom classification (MBC) and functional ambulation category (FAC) for motor function of the upper and lower extremities, respectively. The presence of hypoperfusion on brain SPECT was evaluated in the frontal lobe, temporal lobe, parietal lobe, basal ganglia, thalamus, and cerebellum on both the ipsilesional and contralesional sides. Statistical analysis was performed using multivariate logistic regression, comparing patients in which CST was spared versus interrupted.

Results: Hypoperfusion in the contralesional cerebellum was indicative of poor recovery in both the upper and lower extremities after corona radiata infarction when the CST was interrupted. Additionally, when the CST was preserved, hypoperfusion in the ipsilesional thalamus was indicative of poor recovery of the lower extremities.

Conclusion: Brain SPECT evaluation was shown to be a useful tool for predicting motor outcomes in patients with corona radiata infarcts.

查看原文本刊更多论文

基于脑灌注单光子发射计算机断层扫描预测冠状动脉辐射性梗塞的运动结果。

背景：关于脑灌注单光子发射计算机断层扫描（SPECT）结果与中风患者运动结果相关的信息有限。我们的目的是研究脑SPECT是否可以用于确定放射冠梗死后的运动结果。方法：本研究共招募了89名患者。进行脑SPECT和弥散张量束成像（DTT）来评估放射冠梗死后7-30天内皮质脊髓束（CST）的状态。在梗死发作6个月后测量运动结果，并分别使用改良的Brunstrom分类法（MBC）和功能性行走分类法（FAC）评估上肢和下肢的运动功能。SPECT评估了同侧和对侧额叶、颞叶、顶叶、基底神经节、丘脑和小脑中低灌注的存在。使用多变量逻辑回归进行统计分析，比较CST豁免和中断的患者。结果：当CST中断时，对侧小脑的低灌注表明放射冠梗死后上肢和下肢的恢复较差。此外，当CST被保留时，同侧丘脑的低灌注表明下肢恢复不良。结论：脑SPECT评估被证明是预测放射冠梗死患者运动结果的有用工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Neuroscience 医学-神经科学

CiteScore

5.10

自引率

0.00%

发文量

132

审稿时长

2 months

期刊介绍： The International Journal of Neuroscience publishes original research articles, reviews, brief scientific reports, case studies, letters to the editor and book reviews concerned with problems of the nervous system and related clinical studies, epidemiology, neuropathology, medical and surgical treatment options and outcomes, neuropsychology and other topics related to the research and care of persons with neurologic disorders. The focus of the journal is clinical and transitional research. Topics covered include but are not limited to: ALS, ataxia, autism, brain tumors, child neurology, demyelinating diseases, epilepsy, genetics, headache, lysosomal storage disease, mitochondrial dysfunction, movement disorders, multiple sclerosis, myopathy, neurodegenerative diseases, neuromuscular disorders, neuropharmacology, neuropsychiatry, neuropsychology, pain, sleep disorders, stroke, and other areas related to the neurosciences.