Clinical enzymology of the dog and cat

IF 1.3 4区农林科学 Q2 VETERINARY SCIENCES

Australian Veterinary Journal Pub Date : 2023-09-28 DOI:10.1111/avj.13291

IL Oikonomidis, E Milne

{"title":"Clinical enzymology of the dog and cat","authors":"IL Oikonomidis, E Milne","doi":"10.1111/avj.13291","DOIUrl":null,"url":null,"abstract":"<p>Clinical enzymology studies the enzyme activity in serum or other body fluids for the diagnosis, prognosis or monitoring of a variety of diseases. Clinical enzymology has greatly benefited from advances in technology and is now an integral part of laboratory analysis. However, to maximise the clinical benefits of serum enzyme measurement, clinicians and clinical pathologists must have a good understanding of the pathophysiology behind serum enzyme alterations. They must also be aware of the preanalytical and analytical factors that can affect the accuracy of serum enzyme activity measurement. This review article first covers the basic concepts of clinical enzymology and the general mechanisms related to serum enzyme alterations. Then, the review discusses the potential effects of various preanalytical and analytical factors on enzyme activity measurement. Lastly, it explores the pathophysiology and clinical use of various serum enzymes in canine and feline medicine. The present review article aims to be a comprehensive one-stop source for clinical pathologists and small animal practitioners.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"101 12","pages":"465-478"},"PeriodicalIF":1.3000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/avj.13291","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Veterinary Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/avj.13291","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Clinical enzymology studies the enzyme activity in serum or other body fluids for the diagnosis, prognosis or monitoring of a variety of diseases. Clinical enzymology has greatly benefited from advances in technology and is now an integral part of laboratory analysis. However, to maximise the clinical benefits of serum enzyme measurement, clinicians and clinical pathologists must have a good understanding of the pathophysiology behind serum enzyme alterations. They must also be aware of the preanalytical and analytical factors that can affect the accuracy of serum enzyme activity measurement. This review article first covers the basic concepts of clinical enzymology and the general mechanisms related to serum enzyme alterations. Then, the review discusses the potential effects of various preanalytical and analytical factors on enzyme activity measurement. Lastly, it explores the pathophysiology and clinical use of various serum enzymes in canine and feline medicine. The present review article aims to be a comprehensive one-stop source for clinical pathologists and small animal practitioners.

Abstract Image

查看原文本刊更多论文

狗和猫的临床酶学。

临床酶学研究血清或其他体液中的酶活性，用于诊断、预后或监测各种疾病。临床酶学从技术进步中受益匪浅，现在已成为实验室分析的组成部分。然而，为了最大限度地提高血清酶测量的临床效益，临床医生和临床病理学家必须充分了解血清酶改变背后的病理生理学。他们还必须了解可能影响血清酶活性测量准确性的预分析和分析因素。本文首先介绍了临床酶学的基本概念以及血清酶变化的一般机制。然后，综述了各种预分析和分析因素对酶活性测量的潜在影响。最后，探讨了各种血清酶在犬和猫医学中的病理生理学和临床应用。本综述文章旨在为临床病理学家和小动物从业者提供全面的一站式来源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Australian Veterinary Journal 农林科学-兽医学

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

18-36 weeks

期刊介绍： Over the past 80 years, the Australian Veterinary Journal (AVJ) has been providing the veterinary profession with leading edge clinical and scientific research, case reports, reviews. news and timely coverage of industry issues. AJV is Australia''s premier veterinary science text and is distributed monthly to over 5,500 Australian Veterinary Association members and subscribers.