C–H Bond Functionalization of N-Heteroarenes Mediated by Selectfluor

IF 8.6 2区 化学 Q1 Chemistry
Angel H. Romero
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引用次数: 1

Abstract

Herein, recent developments for Selectfluor-mediated C–H functionalization of N-heteroarenes are described. This type of C–H bond activation is an attractive and competitive alternative to traditional methodologies, allowing the functionalization of a variety of chemical functions. In addition, Selectfluor is a more sustainable and economically accessible oxidant compared with expensive/toxic metals or hazardous peroxides. For a practical understanding, the current review classified systematically the reported strategies in four subsections as follows: (1) carbon–carbon formation, (2) carbon–nitrogen bond formation, (3) carbon–chalcogen bond, and (4) carbon–halogen bond formation. Mechanistic aspects and reaction conditions are fully discussed to provide an understanding of the aspects that govern C–H functionalization in N-heteroarenes mediated by Selectfluor.

Graphical Abstract

Abstract Image

选择性荧光介导N-杂芳烃的C-H键功能化。
本文介绍了选择性荧光介导的N-杂芳烃的C-H功能化的最新进展。这种类型的C-H键活化是传统方法的一种有吸引力和竞争力的替代方法,允许各种化学功能的功能化。此外,与昂贵/有毒的金属或危险的过氧化物相比,Selectfluor是一种更可持续、更经济的氧化剂。为了便于实际理解,本综述将所报道的策略系统地分为四个子部分,如下:(1)碳-碳形成,(2)碳-氮键形成,(3)碳-硫族键和(4)碳-卤键形成。充分讨论了机理方面和反应条件,以提供对由Selectfluor介导的N-杂芳烃中C-H官能化的控制方面的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Topics in Current Chemistry
Topics in Current Chemistry 化学-化学综合
CiteScore
11.70
自引率
1.20%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Topics in Current Chemistry provides in-depth analyses and forward-thinking perspectives on the latest advancements in chemical research. This renowned journal encompasses various domains within chemical science and their intersections with biology, medicine, physics, and materials science. Each collection within the journal aims to offer a comprehensive understanding, accessible to both academic and industrial readers, of emerging research in an area that captivates a broader scientific community. In essence, Topics in Current Chemistry illuminates cutting-edge chemical research, fosters interdisciplinary collaboration, and facilitates knowledge-sharing among diverse scientific audiences.
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