Polyalkoxy-substituted nitrostilbenes in the synthesis of lamellarin analogs. Formal synthesis of lamellarin H

IF 1.7 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
E. A. Silyanova, A. S. Maksimenko, M. D. Brunner, I. A. Koblov, V. P. Kislyi, A. V. Samet, V. V. Semenov
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引用次数: 0

Abstract

Lamellarin D trimethyl ether was prepared by 1,3-dipolar cycloaddition of 6,7-dimethoxyisoquinolinium ylide to pentamethoxy-substituted nitrostilbene followed by a lactone ring closure in the intermediate cycloadduct. This approach allowed a formal synthesis of lamellarin H.

聚烷氧基取代的亚硝基二苯乙烯在合成薄片蛋白类似物中的应用。薄层素H的形式合成
通过6,7-二甲氧基异喹啉叶立德与五甲氧基取代的亚硝基二苯乙烯的1,3-偶极环加成,然后在中间体环加成物中闭合内酯环,制备了片状D三甲基醚。这种方法允许正式合成薄片蛋白H。
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来源期刊
Russian Chemical Bulletin
Russian Chemical Bulletin 化学-化学综合
CiteScore
2.70
自引率
47.10%
发文量
257
审稿时长
3-8 weeks
期刊介绍: Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.
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