Prevalence and sociodemographic characteristics associated with benzodiazepines use among community dwelling older adults: the Bambuí Health and Aging Study (BHAS).

Jussara Mendonça Alvarenga, Antônio Ignácio de Loyola Filho, Josélia Oliveira Araújo Firmo, Maria Fernanda Lima-Costa, Elizabeth Uchoa
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引用次数: 6

Abstract

Objectives: To assess the prevalence and sociodemographic characteristics associated with benzodiazepine use among community-dwelling older adults.

Method: 1606 subjects, aged > 60 years, corresponding to 92% of the residents of Bambuí city, participated in this study. The information about medication use was obtained by means of a standard interview and the review of medication packaging. Substances were classified using the Anatomical Therapeutic Chemical Index.

Results: The prevalence of benzodiazepine current use was 21.7% (26.7% among females and 14.0% among males). From these, 68.7% had been taking the medication for over one year, 31.3% for over five years and 53.2% were using long half-life benzodiazepines. The medication most frequently used was bromazepam (35.6%), followed by diazepam (22.5%), clonazepam (12.6%) and lorazepam (7.8%). After adjustment for confounders, female gender (RP = 1.93; CI95% = 1.51-2.46) was the only sociodemographic characteristic found to be independently associated with substance consumption.

Conclusions: The prevalence of benzodiazepine use in the study population was high, but within the variation observed in developed countries. Chronic use of benzodiazepines and long half-life medications predominated.

社区居住的老年人中与苯二氮卓类药物使用相关的患病率和社会人口学特征:Bambuí健康与老龄化研究(BHAS)
目的:评估社区居住老年人苯二氮卓类药物使用的患病率和社会人口学特征。方法:1606名年龄> 60岁的受试者参与本研究,占Bambuí市居民的92%。通过标准的访谈和药品包装的审查获得药物使用信息。使用解剖治疗化学指数对物质进行分类。结果:目前苯二氮卓类药物使用率为21.7%(女性26.7%,男性14.0%)。其中68.7%的人服药超过一年,31.3%的人服药超过五年,53.2%的人服用半衰期较长的苯二氮卓类药物。用药最多的是溴西泮(35.6%),其次是地西泮(22.5%)、氯硝西泮(12.6%)和劳拉西泮(7.8%)。校正混杂因素后,女性(RP = 1.93;CI95% = 1.51-2.46)是发现的唯一与物质消耗独立相关的社会人口学特征。结论:苯二氮卓类药物在研究人群中的使用率很高,但在发达国家观察到的差异范围内。长期使用苯二氮卓类药物和长半衰期药物占主导地位。
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