RNA interference and chemically modified siRNAs.

Nucleic acids research. Supplement (2001) Pub Date : 2003-01-01 DOI:10.1093/nass/3.1.115

Muthiah Manoharan

引用次数: 17

Abstract

RNA interference (RNAi) represents one of the most promising new frontiers in drug discovery. Short double-stranded RNA molecules are able to sequence-specifically inhibit expression of genes. This young technology offers both opportunities and challenges to nucleic acid chemists.

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RNA干扰和化学修饰sirna。

RNA干扰(RNAi)是药物发现中最有前途的新领域之一。短双链RNA分子能够序列特异性地抑制基因的表达。这项年轻的技术为核酸化学家提供了机遇和挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nucleic acids research. Supplement (2001)

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