The mechanism of intestinal utilization of monoglycerides

Jerry L. Brown , John M. Johnston
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引用次数: 33

Abstract

  • 1.

    1. The intact utilization of 1-monopalmitin by intestinal mucosal enzymes for the synthesis of triglycerides has been demonstrated.

  • 2.

    2. The enzyme does not demonstrate a specificity for the d or l isomer

  • 3.

    3. The first acylation of 1-monopalmitin occurs at the corresponding pirmary hydroxy group forming the 1,3-diglyceride intermediate.

  • 4.

    4. The subcellular location and optimal requirements of the enzyme system catalyzing the acylation have been determined.

单甘油酯的肠道利用机制
1.1. 已证实肠粘膜酶完整地利用1-单磷酸酶合成甘油三酯。该酶对d或l异构体没有特异性3.3。1-单甘油三酯的第一次酰化发生在相应的初级羟基上,形成1,3-二甘油三酯中间体。已经确定了催化酰化的酶系统的亚细胞位置和最佳要求。
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