Personnel protection strategy for healthcare workers in Wuhan during the COVID-19 epidemic.

IF 5 4区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Precision Clinical Medicine Pub Date : 2020-07-20 eCollection Date: 2020-09-01 DOI:10.1093/pcmedi/pbaa024

Fan Fan Hou, Fuling Zhou, Xin Xu, Daowen Wang, Gang Xu, Tao Jiang, Sheng Nie, Xiaoyan Wu, Chanjun Ren, Guangyu Wang, Johnson Yiu-Nam Lau, Xinghuan Wang, Kang Zhang

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引用次数: 8

Abstract

Objective: To identify the effectiveness of a personnel protection strategy in protection of healthcare workers from SARS-CoV-2 infection.

Design: During the COVID-19 pandemic, 943 healthcare staff sent from Guangzhou to Wuhan to care for patients with suspected/confirmed COVID-19 received infection precaution training before their mission and were equipped with Level 2/3 personal protective equipment (PPE), in accordance with guidelines from the National Health Commission of China. We conducted a serological survey on the cumulative attack rate of SARS-CoV-2 among the healthcare workers sent to Wuhan and compared the seropositive rate to that in local healthcare workers from Wuhan and Jingzhou.

Results: Serial tests for SARS-CoV-2 RNA and tests for SARS-CoV-2 immunoglobulin M and G after the 6-8 week mission revealed a zero cumulative attack rate. Among the local healthcare workers in Wuhan and Jingzhou of Hubei Province, 2.5% (113 out of 4495) and 0.32% (10 out of 3091) had RT-PCR confirmed COVID-19, respectively. The seropositivity for SARS-CoV-2 antibodies (IgG, IgM, or both IgG/IgM positive) was 3.4% (53 out of 1571) in local healthcare workers from Wuhan with Level 2/3 PPE working in isolation areas and 5.4% (126 out of 2336) in healthcare staff with Level 1 PPE working in non-isolation medical areas, respectively.

Conclusions and relevance: Our study confirmed that adequate training/PPE can protect medical personnel against SARS-CoV-2.

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COVID-19疫情期间武汉市医护人员防护策略

目的:探讨人员防护策略在医护人员防范SARS-CoV-2感染中的有效性。设计:在2019冠状病毒病大流行期间，根据中国国家卫生健康委员会的指导方针，从广州派往武汉照顾COVID-19疑似/确诊患者的943名医护人员在任务前接受了感染预防培训，并配备了2/3级个人防护装备(PPE)。对外派武汉医务人员进行SARS-CoV-2累计发病情况血清学调查，并与武汉、荆州当地医务人员进行血清学阳性率比较。结果:在6-8周的任务后，对SARS-CoV-2 RNA和SARS-CoV-2免疫球蛋白M和G的系列检测显示，累积发病率为零。湖北省武汉市和荆州市当地医务人员中，4495人中有113人，占2.5%;3091人中有10人，占0.32%。在隔离区域工作的武汉本地2/3级个人防护装备医务人员血清中SARS-CoV-2抗体(IgG、IgM或IgG/IgM均阳性)阳性率为3.4%(1571人中53人)，在非隔离医疗区域工作的1级个人防护装备医务人员血清中阳性率为5.4%(2336人中126人)。结论及相关性:本研究证实，适当的培训/个人防护装备可以保护医务人员免受SARS-CoV-2的侵害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Precision Clinical Medicine MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

10.80

自引率

0.00%

发文量

审稿时长

5 weeks

期刊介绍： Precision Clinical Medicine (PCM) is an international, peer-reviewed, open access journal that provides timely publication of original research articles, case reports, reviews, editorials, and perspectives across the spectrum of precision medicine. The journal's mission is to deliver new theories, methods, and evidence that enhance disease diagnosis, treatment, prevention, and prognosis, thereby establishing a vital communication platform for clinicians and researchers that has the potential to transform medical practice. PCM encompasses all facets of precision medicine, which involves personalized approaches to diagnosis, treatment, and prevention, tailored to individual patients or patient subgroups based on their unique genetic, phenotypic, or psychosocial profiles. The clinical conditions addressed by the journal include a wide range of areas such as cancer, infectious diseases, inherited diseases, complex diseases, and rare diseases.