An Unusual Solitary Fibrous Tumor of the Ischiorectal Region.

IF 1.4 Q4 GASTROENTEROLOGY & HEPATOLOGY
Gastroenterology Research Pub Date : 2022-10-01 Epub Date: 2022-10-19 DOI:10.14740/gr1539
Mahmoud R A Hussein, Abdullah Saad Alqahtani, Mubarak Mohammed Al-Shraim, Yahia Ibraheem Assiri, Feras O Ahmed, Mohammed Jalwi Korkoman, Ahmed Y Al-Ameer, Asmaa M Ahmed
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引用次数: 0

Abstract

Solitary fibrous tumors (SFTs) are rare fibroblastic/myofibroblastic proliferations that occur in a wide range of anatomical sites. These tumors have nonspecific clinical presentations often with unpredictable biological behavior. SFTs can be slow growing low-risk tumors or rapidly growing high-risk tumors. They show a wide variety of histological features and typically are characterized by NAB2-STAT6 fusion. SFTs of the ischiorectal fossa are rare, with few studies reported in the literature to date. Here, we report a 90-year-old male who had a road traffic accident in October 2018. A pelvic computed tomography (CT) revealed a mass measuring 3.5 × 2.5 cm in the right ischiorectal fossa. Histopathology of the CT-guided biopsies confirmed the diagnosis of low-grade SFT. No surgical intervention was needed since the patient was asymptomatic. In January 2022, a follow-up CT showed a gradual increase in tumor size (5 × 3.5 × 3 cm), but not infiltrating the surrounding structures. However, the patient complained of constipation, which warranted a surgical excision of the mass. Subsequently, immunohistological examination reconfirmed the diagnosis of low-risk SFT. Here, we discussed the clinicopathological features of the case and the relevant literature about pelvic SFTs. In conclusion, SFTs should be considered in the differential diagnosis of any ischiorectal mass. It is recommended that tissue samples be obtained, and immunohistology should be performed.

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坐骨直肠区罕见的孤立性纤维性肿瘤。
孤立性纤维性肿瘤(SFTs)是罕见的纤维母细胞/肌纤维母细胞增生,发生在广泛的解剖部位。这些肿瘤具有非特异性的临床表现,通常具有不可预测的生物学行为。SFTs可以是生长缓慢的低风险肿瘤,也可以是生长迅速的高风险肿瘤。它们表现出多种组织学特征,并以NAB2-STAT6融合为典型特征。坐骨直肠窝的SFTs是罕见的,迄今为止文献报道的研究很少。在这里,我们报告了一名90岁的男性,他在2018年10月发生了一起道路交通事故。骨盆计算机断层扫描(CT)显示在右侧坐骨直肠窝有3.5 × 2.5 cm的肿块。ct引导下的组织病理学证实了低级别SFT的诊断。由于患者无症状,无需手术干预。2022年1月随访CT示肿瘤大小逐渐增大(5 × 3.5 × 3cm),但未浸润周围结构。然而,病人主诉便秘,需要手术切除肿块。随后,免疫组织学检查再次确诊为低危性SFT。在此,我们讨论了该病例的临床病理特征和盆腔SFTs的相关文献。总之,在任何坐骨直肠肿块的鉴别诊断中都应考虑SFTs。建议获得组织样本,并进行免疫组织学检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gastroenterology Research
Gastroenterology Research GASTROENTEROLOGY & HEPATOLOGY-
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