Nonsurgical Treatment of Peri-implantitis Using a Chitosan Brush with Adjunctive Chemical Decontaminants- A Retrospective Case Series.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-11-01 DOI:10.11607/jomi.9602

Roy Stefan Samuelsson, Anders Kristian Valnes, Johan Caspar Wohlfahrt

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引用次数: 0

Abstract

Purpose: To evaluate the effect of a simple nonsurgical procedure for the treatment of peri-implantitis.

Materials and methods: A total of 30 implants across 24 patients diagnosed with moderate to advanced peri-implantitis were treated using a chitosan brush with adjunctive chemicals, ie, 3% hydrogen peroxide and a tetracycline slurry. The treatment was performed a total of three times, with intervals of approximately 3 weeks.

Results: Results showed improvement in both the clinical attachment level (CAL) and bleeding on probing score between the baseline and the re-examinations between 9 months and up to 43 months (mean 26.8 months) after treatment. The mean CAL at baseline was 3.4 mm (range: 1 to 8 mm), while the mean CAL during the final examination was 1.4 mm (range: 0 to 5 mm), demonstrating a mean reduction of CAL of 2 mm (range: 1 to 7 mm; P < .001). Of the analyzed implant sites, 72% demonstrated radiographic signs of osseous defect fill varying between 0.1 and 2.2 mm (mean: 1.0 mm).

Conclusion: The results show that this novel treatment strategy may serve as a nonsurgical alternative to reduce parameters of inflammation around implants with moderate to advanced peri-implantitis.

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壳聚糖刷刷辅助化学去污非手术治疗种植体周围炎-回顾性病例系列。

目的:评价一种简单的非手术方法治疗种植体周围炎的效果。材料和方法:24例诊断为中晚期种植体周围炎的患者共30颗种植体，使用壳聚糖刷刷和辅助化学物质(即3%过氧化氢和四环素浆液)进行治疗。治疗共进行三次，间隔约为3周。结果:治疗后9个月至43个月(平均26.8个月)，临床附着水平(CAL)和出血探查评分在基线和复诊期间均有改善。基线时的平均CAL为3.4 mm(范围:1至8 mm)，而期末检查时的平均CAL为1.4 mm(范围:0至5 mm)，表明CAL平均减少2mm(范围:1至7 mm;P < 0.001)。在分析的种植体部位中，72%显示骨缺损填充的x线征象在0.1至2.2 mm之间(平均:1.0 mm)。结论:结果表明，这种新的治疗策略可以作为一种非手术替代方法，减少种植体周围炎症参数，并伴有中度至晚期种植体周围炎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.