Smart DNA nanogel coated polydopamine nanoparticle with high drug loading for chemo-photothermal therapy of cancer.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-11-16 DOI:10.1116/6.0002170

Shiyu Zang, Xunxun Deng, Jiamian Wang, Yanqiu Zhao, Shuo Wu

引用次数: 2

Abstract

A smart deoxyribose nucleic acid nanogel coated polydopamine nanosphere hybrid was designed for chemo-photothermal therapy of cancer. The nanohybrid showed good colloid stability, narrow size distribution, high drug loading, good biocompatibility, and high photothermal conversion efficiency, and could release the drug on desired tumor sites.

查看原文本刊更多论文

智能DNA纳米凝胶包被高载药量的聚多巴胺纳米颗粒用于癌症的化学光热治疗。

设计了一种智能脱氧核糖核酸纳米凝胶包被聚多巴胺纳米球复合物，用于肿瘤的化学光热治疗。该纳米杂化物具有胶体稳定性好、粒径分布窄、载药量大、生物相容性好、光热转化效率高等特点，可在肿瘤特定部位释放药物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.