{"title":"Secular trends of birth weight and its associations with obesity and hypertension among Southern Chinese children and adolescents.","authors":"Xiaoying He, Zixian Shao, Jiajia Jing, Xiaotong Wang, Suhua Xu, Miao Wu, Yanna Zhu","doi":"10.1515/jpem-2021-0430","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The association of low or high birth weight (L/HBW) with obesity and hypertension in childhood remains unclear. We aimed to identify the secular trend of birth weight distribution and its relationship to obesity and hypertension in Southern Chinese children and adolescents.</p><p><strong>Methods: </strong>6,561 individuals (6-17-year-old) were enrolled by multistage cluster sampling to observed the trend of birth weight distribution and its associated factors. 1,218 were further selected by group matching to investigate the correlation between birth weight and obesity or hypertension.</p><p><strong>Results: </strong>Between 1997 and 2008, a significant decline in the LBW rate and no significant change in the HBW rate was found. LBW was associated with maternal BMI<18 kg/m<sup>2</sup> (OR1.79, 95% CI 1.08-2.97) during pregnancy, while maternal BMI between 25.0 and 27.9 kg/m<sup>2</sup> (OR1.62, 95% CI 1.04-2.52) and paternal BMI>28 kg/m<sup>2</sup> (OR1.64, 95% CI 1.02-2.63) during pregnancy were associated with HBW. The prevalence of obesity was significantly higher with HBW than normal birth weight (NBW) or LBW (16.73, 6.25 and 5.50%, respectively). The prevalence rates of suspected hypertension were 1.62, 1.25 and 1.49% among LBW, NBW and HBW, respectively (p>0.05). LBW decreased the risks of childhood overweight (OR0.31, 95% CI 0.18-0.54), but had no effect on suspected hypertension. HBW increased the risks of childhood obesity (OR2.19, 95% CI 1.50-3.20), but decreased the risks of suspected hypertension (OR0.22, 95% CI 0.09-0.58).</p><p><strong>Conclusions: </strong>HBW was positively associated with childhood obesity, and parental BMIs management might be one of the measurements to control birth weight to lessen childhood obesity.</p>","PeriodicalId":520684,"journal":{"name":"Journal of pediatric endocrinology & metabolism : JPEM","volume":" ","pages":"1487-1496"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pediatric endocrinology & metabolism : JPEM","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/jpem-2021-0430","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/12/16 0:00:00","PubModel":"Print","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Objectives: The association of low or high birth weight (L/HBW) with obesity and hypertension in childhood remains unclear. We aimed to identify the secular trend of birth weight distribution and its relationship to obesity and hypertension in Southern Chinese children and adolescents.
Methods: 6,561 individuals (6-17-year-old) were enrolled by multistage cluster sampling to observed the trend of birth weight distribution and its associated factors. 1,218 were further selected by group matching to investigate the correlation between birth weight and obesity or hypertension.
Results: Between 1997 and 2008, a significant decline in the LBW rate and no significant change in the HBW rate was found. LBW was associated with maternal BMI<18 kg/m2 (OR1.79, 95% CI 1.08-2.97) during pregnancy, while maternal BMI between 25.0 and 27.9 kg/m2 (OR1.62, 95% CI 1.04-2.52) and paternal BMI>28 kg/m2 (OR1.64, 95% CI 1.02-2.63) during pregnancy were associated with HBW. The prevalence of obesity was significantly higher with HBW than normal birth weight (NBW) or LBW (16.73, 6.25 and 5.50%, respectively). The prevalence rates of suspected hypertension were 1.62, 1.25 and 1.49% among LBW, NBW and HBW, respectively (p>0.05). LBW decreased the risks of childhood overweight (OR0.31, 95% CI 0.18-0.54), but had no effect on suspected hypertension. HBW increased the risks of childhood obesity (OR2.19, 95% CI 1.50-3.20), but decreased the risks of suspected hypertension (OR0.22, 95% CI 0.09-0.58).
Conclusions: HBW was positively associated with childhood obesity, and parental BMIs management might be one of the measurements to control birth weight to lessen childhood obesity.
目的:低或高出生体重(L/HBW)与儿童肥胖和高血压的关系尚不清楚。我们的目的是确定中国南方儿童和青少年出生体重分布的长期趋势及其与肥胖和高血压的关系。方法:采用多阶段整群抽样方法,对6561名6 ~ 17岁儿童进行出生体重分布趋势及相关因素分析。通过分组配对,进一步选择1218例新生儿进行出生体重与肥胖或高血压的相关性研究。结果:1997 - 2008年间,低体重率显著下降,而高体重率无显著变化。妊娠期LBW与母体BMI2相关(OR1.79, 95% CI 1.08-2.97),而妊娠期母体BMI在25.0 ~ 27.9 kg/m2之间(OR1.62, 95% CI 1.04-2.52)和父亲BMI>28 kg/m2 (OR1.64, 95% CI 1.02-2.63)与HBW相关。肥胖患病率HBW明显高于正常出生体重(NBW)和LBW(分别为16.73%、6.25%和5.50%)。LBW、NBW和HBW的疑似高血压患病率分别为1.62%、1.25和1.49% (p>0.05)。低体重降低了儿童超重的风险(OR0.31, 95% CI 0.18-0.54),但对疑似高血压没有影响。HBW增加了儿童肥胖的风险(OR2.19, 95% CI 1.50-3.20),但降低了疑似高血压的风险(OR0.22, 95% CI 0.09-0.58)。结论:HBW与儿童肥胖呈正相关,父母bmi管理可能是控制出生体重减轻儿童肥胖的措施之一。