3.0-T closed MR-guided microwave ablation for HCC located under the hepatic dome: a single-center experience.

IF 3

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group Pub Date : 2022-12-01 DOI:10.1080/02656736.2022.2107717

Kaihao Xu, Zhaonan Li, Chaoyan Wang, Chuan Tian, Dechao Jiao, Xinwei Han, Yan Yan

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引用次数: 1

Abstract

Purpose: To analyze the clinical safety and efficacy of 3.0-T closed MR-guided microwave ablation (MWA) for the treatment of HCC located under the hepatic dome.

Methods: From May 2018 to October 2020, 49 patients with 74 HCCs located under the hepatic dome underwent MWA using 3.0-T closed MR guidance. The technical success rate, operative time, complete ablation (CA) rate, complications, local tumor progression (LTP), tumor-free survival (TFS) and overall survival (OS) were examined. Routine blood analysis, liver/kidney function and alpha fetoprotein (AFP) and protein induced by vitamin k absent or antagonist (PIVKA) levels were compared before and 2 months after MWA.

Results: All patients underwent MWA successfully, including 10 patients who underwent general anesthesia. The technical success rate was 100% without major complications. The CA rate was 95.9% (71/74) at the 2-month evaluation. The LTP rate was 2.7% during the median follow-up of 17.8 months (range: 4-43 months); the 6-, 12-, 18-month TFS rates were 97.8, 90.6, 68.1%, respectively, and the 6-, 12-, 18-month OS rates were 100, 97.6, 92.1%, respectively. There were no significant changes in routine blood tests and liver/kidney function (p > 0.05), while the AFP and PIVKA level decreased significantly at 2 months (p < 0.05).

Conclusion: 3.0-T MR-guided MWA is safe and feasible for HCC lesions located under the hepatic dome.

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3.0-T磁共振引导下封闭微波消融术治疗肝穹窿下肝癌:单中心体验

目的:分析3.0 t磁共振引导下闭式微波消融术(MWA)治疗肝穹下肝细胞癌的临床安全性和有效性。方法:2018年5月至2020年10月，49例74例位于肝穹下的hcc患者采用3.0-T封闭MR引导行MWA。观察技术成功率、手术时间、完全消融(CA)率、并发症、局部肿瘤进展(LTP)、无瘤生存(TFS)和总生存(OS)。比较MWA前后2个月的血常规、肝肾功能、甲胎蛋白(AFP)和维生素k缺失或拮抗剂诱导的蛋白(PIVKA)水平。结果:所有患者均成功行MWA手术，其中10例患者行全身麻醉。技术成功率100%，无重大并发症。2个月时CA率为95.9%(71/74)。在17.8个月(范围:4-43个月)的中位随访期间，LTP率为2.7%;6、12、18个月TFS分别为97.8、90.6、68.1%，6、12、18个月OS分别为100、97.6、92.1%。两组患者血常规、肝肾功能无明显变化(p > 0.05)， 2个月时AFP、PIVKA水平明显下降(p)。结论:3.0 t mr引导下MWA治疗位于肝球下的HCC是安全可行的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

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