{"title":"Progress in the Study of Optical Probes for the Detection of Formaldehyde.","authors":"Xuexuan Xu, Erpei Yang, Yanyan Chen","doi":"10.1080/10408347.2022.2107870","DOIUrl":null,"url":null,"abstract":"<p><p>Formaldehyde, one of the simplest reactive carbonyl substances, is involved in many physiological and pathological processes in living organisms. There is a large amount of data showing that abnormal elevation of formaldehyde is associated with a variety of diseases in the body, such as neurodegenerative diseases, Alzheimer's disease, cardiovascular diseases and cancer, and is also a representative carcinogen, so monitoring formaldehyde is of great importance for disease diagnosis and treatment. In this review, In this paper, we summarize and classify the last ten years of probes for the detection of formaldehyde according to different reaction mechanisms and discuss the structures and applications of the probes. Finally, we briefly describe the challenges and possible solutions in this field. We believe that more new probes provide powerful tools to study the function of formaldehyde in living systems.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Critical reviews in analytical chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/10408347.2022.2107870","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/8/8 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Formaldehyde, one of the simplest reactive carbonyl substances, is involved in many physiological and pathological processes in living organisms. There is a large amount of data showing that abnormal elevation of formaldehyde is associated with a variety of diseases in the body, such as neurodegenerative diseases, Alzheimer's disease, cardiovascular diseases and cancer, and is also a representative carcinogen, so monitoring formaldehyde is of great importance for disease diagnosis and treatment. In this review, In this paper, we summarize and classify the last ten years of probes for the detection of formaldehyde according to different reaction mechanisms and discuss the structures and applications of the probes. Finally, we briefly describe the challenges and possible solutions in this field. We believe that more new probes provide powerful tools to study the function of formaldehyde in living systems.
期刊介绍：
Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area.
This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following:
· chemical analysis;
· instrumentation;
· chemometrics;
· analytical biochemistry;
· medicinal analysis;
· forensics;
· environmental sciences;
· applied physics;
· and material science.
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