The relationship between radial artery spasm and adropin levels in patients undergoing transradial coronary angiography.

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Fuat Bice, Mehmet Eyuboglu, Zeliha Cansel Ozmen, Baris Acikel, Mustafa Yilmaz, Metin Karayakali, Kayihan Karaman, Cagri Zorlu, Atac Celik
{"title":"The relationship between radial artery spasm and adropin levels in patients undergoing transradial coronary angiography.","authors":"Fuat Bice,&nbsp;Mehmet Eyuboglu,&nbsp;Zeliha Cansel Ozmen,&nbsp;Baris Acikel,&nbsp;Mustafa Yilmaz,&nbsp;Metin Karayakali,&nbsp;Kayihan Karaman,&nbsp;Cagri Zorlu,&nbsp;Atac Celik","doi":"10.34172/jcvtr.2022.15","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Transradial coronary angiography (TRA) is associated with a lower incidence of bleeding rate and access site complications and is associated with better outcomes compared to transfemoral angiography. However, radial artery spasm (RAS) is an important limitation of TRA procedures. Little is known regarding the relationship of serum vasodilator and inflammatory markers with RAS. Therefore, the present study aimed to investigate the association between serum adropin level and RAS in patients undergoing TRA. <b><i>Methods:</i></b> From February 2020 to January 2021, 39 consecutive patients who underwent elective daiagnostic TRA and experienced RAS during the procedure, and 42 age and sex matched controls who did not experience RAS were prospectively included into the study. The groups were compared regarding serum adropin levels and inflammatory markers. <b><i>Results:</i></b> Although adropin levels were found to be lower in the RAS group, this difference was not statistically significant between the the patients with RAS and controls (14.9 vs. 16.1, <i>P</i>=0.105). However, inflammatory parameters monocyte count and MHR (monocyte/HDL cholesterol ratio) were found to be statistically significantly higher in the RAS group compared to controls (<i>P</i>=0.001 and <i>P</i>=0.010, respectively). Moreover, a significant positive correlation was found between the monocyte count and RAS (r:0.360, <i>P</i><0.001), and between MHR and RAS (r:0.288, <i>P</i>=0.009). Furthermore, multivariate analysis demonstrated that monocyte count (OR:1.671, 95%CI:1.312-2.094, <i>P</i>=0.001) and MHR (OR:1.116, 95%CI:1.054-1.448, <i>P</i>=0.022) were found to be independent predictors of RAS. <b><i>Conclusion:</i></b> Serum vasodilator and inflammatory markers may be useful in the prediction of RAS in patients undergoing TRA procedures.</p>","PeriodicalId":15207,"journal":{"name":"Journal of Cardiovascular and Thoracic Research","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339735/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular and Thoracic Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jcvtr.2022.15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/6/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 1

Abstract

Introduction: Transradial coronary angiography (TRA) is associated with a lower incidence of bleeding rate and access site complications and is associated with better outcomes compared to transfemoral angiography. However, radial artery spasm (RAS) is an important limitation of TRA procedures. Little is known regarding the relationship of serum vasodilator and inflammatory markers with RAS. Therefore, the present study aimed to investigate the association between serum adropin level and RAS in patients undergoing TRA. Methods: From February 2020 to January 2021, 39 consecutive patients who underwent elective daiagnostic TRA and experienced RAS during the procedure, and 42 age and sex matched controls who did not experience RAS were prospectively included into the study. The groups were compared regarding serum adropin levels and inflammatory markers. Results: Although adropin levels were found to be lower in the RAS group, this difference was not statistically significant between the the patients with RAS and controls (14.9 vs. 16.1, P=0.105). However, inflammatory parameters monocyte count and MHR (monocyte/HDL cholesterol ratio) were found to be statistically significantly higher in the RAS group compared to controls (P=0.001 and P=0.010, respectively). Moreover, a significant positive correlation was found between the monocyte count and RAS (r:0.360, P<0.001), and between MHR and RAS (r:0.288, P=0.009). Furthermore, multivariate analysis demonstrated that monocyte count (OR:1.671, 95%CI:1.312-2.094, P=0.001) and MHR (OR:1.116, 95%CI:1.054-1.448, P=0.022) were found to be independent predictors of RAS. Conclusion: Serum vasodilator and inflammatory markers may be useful in the prediction of RAS in patients undergoing TRA procedures.

经桡动脉冠状动脉造影患者桡动脉痉挛与肾上腺素水平的关系。
简介:与经股动脉造影相比,经桡动脉冠状动脉造影(TRA)与较低的出血率和通路并发症发生率相关,并且与更好的结果相关。然而,桡动脉痉挛(RAS)是TRA手术的重要限制。关于血清血管扩张剂和炎症标志物与RAS的关系知之甚少。因此,本研究旨在探讨TRA患者血清adropin水平与RAS之间的关系。方法:从2020年2月至2021年1月,39例连续接受选择性诊断性TRA并在手术过程中经历RAS的患者,以及42例年龄和性别匹配的未经历RAS的对照组前瞻性纳入研究。比较两组血清促肾上腺素水平和炎症标志物。结果:RAS组虽然adropin水平较低,但RAS组与对照组的差异无统计学意义(14.9 vs. 16.1, P=0.105)。然而,与对照组相比,RAS组炎症参数单核细胞计数和单核细胞/高密度脂蛋白胆固醇比率(MHR)均有统计学意义上的升高(P=0.001和P=0.010)。单核细胞计数与RAS呈显著正相关(r:0.360, PP=0.009)。此外,多因素分析表明,单核细胞计数(OR:1.671, 95%CI:1.312-2.094, P=0.001)和MHR (OR:1.116, 95%CI:1.054-1.448, P=0.022)是RAS的独立预测因子。结论:血清血管扩张剂和炎症标志物可用于预测TRA患者的RAS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Cardiovascular and Thoracic Research
Journal of Cardiovascular and Thoracic Research CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.00
自引率
0.00%
发文量
22
审稿时长
7 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信