Orthotopic kidney transplantation survival and complications: systematic review and meta-analysis.

IF 1.3 Q3 UROLOGY & NEPHROLOGY

Arab Journal of Urology Pub Date : 2022-06-17 eCollection Date: 2022-01-01 DOI:10.1080/2090598X.2022.2090133

Carlos Alfredo Castillo-Delgado, Herney Andrés García-Perdomo, Mireia Musquera, Antonio Alcaraz

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引用次数: 0

Abstract

Purpose: To determine graft and patient survival and adverse events in patients who undergo orthotopic kidney transplantation.

Methods: We performed a systematic review and meta-analysis. We search in Medline, Embase, and Central from inception to nowadays. We included observational studies with patients who undergo orthotopic kidney transplantation. The primary outcomes were overall patient and graft survival. We pooled the information in a frequency meta-analysis with a 95% CI. We analyzed bias with the STROBE statement.

Results: Of the 106 papers initially retrieved, four met the inclusion criteria. Vascular and urinary tract complications were reported in 19% and 15%, respectively. The overall patient survival was 92% 95%CI (88% to 95%), I2 = 0%, and the overall graft survival was 88% 95 CI (83% to 91%), I2 = 0%.

Conclusion: Our analysis showed a high survival rate in patients and kidney grafts after orthotopic kidney transplantation, with a similar complication rate compared to a heterotopic kidney transplant.

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正位肾移植的存活率和并发症：系统回顾和荟萃分析。

目的：确定接受正位肾移植患者的移植物和患者存活率以及不良事件：我们进行了系统回顾和荟萃分析。我们在 Medline、Embase 和 Central 中检索了从开始到现在的研究。我们纳入了对接受异位肾移植患者的观察性研究。主要结果是患者和移植物的总体存活率。我们在频率荟萃分析中汇总了信息，并得出了 95% 的 CI。我们使用 STROBE 声明分析了偏倚情况：在最初检索到的 106 篇论文中，有 4 篇符合纳入标准。血管并发症和尿路并发症分别占19%和15%。患者总存活率为 92% 95%CI (88% to 95%)，I2 = 0%，移植物总存活率为 88% 95%CI (83% to 91%)，I2 = 0%：我们的分析表明，正位肾移植后患者和移植物的存活率较高，并发症发生率与异位肾移植相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arab Journal of Urology UROLOGY & NEPHROLOGY-

CiteScore

2.80

自引率

0.00%

发文量

期刊介绍： The Arab Journal of Urology is a peer-reviewed journal that strives to provide a high standard of research and clinical material to the widest possible urological community worldwide. The journal encompasses all aspects of urology including: urological oncology, urological reconstructive surgery, urodynamics, female urology, pediatric urology, endourology, transplantation, erectile dysfunction, and urinary infections and inflammations. The journal provides reviews, original articles, editorials, surgical techniques, cases reports and correspondence. Urologists, oncologists, pathologists, radiologists and scientists are invited to submit their contributions to make the Arab Journal of Urology a viable international forum for the practical, timely and state-of-the-art clinical urology and basic urological research.