Efficacy and safety of low-intensity extracorporeal shock wave therapy versus on-demand tadalafil for erectile dysfunction.

IF 1.3 Q3 UROLOGY & NEPHROLOGY

Arab Journal of Urology Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI:10.1080/2090598X.2022.2090134

Fouad Zanaty, Atef Badawy, Hossam Kotb, Fatma Elsarfy, Baher Salman

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引用次数: 0

Abstract

Objective: To compare outcomes of low-intensity extracorporeal shock wave therapy (LIESWT) versus 20 mg of Tadalafil in Erectile dysfunction (ED) patients.

Materials and methods: We performed a prospective study of 51 men with ED. Twenty-five were in the LIESWT group and 26 in the Tadalafil group. Patients in the LIESWT group received 6 sessions (2 per week) with an average of 6,000 shocks per session with the PiezoWave² unit. Other patients self-administered Tadalafil on demand. The outcomes were assessed using the International Index of Erectile Function (IIEF-5) score, Erection Hardness Score (EHS) and Self-Esteem And Relationship (SEAR) questionnaire before, at 6 and 12 weeks after treatment. Treatment-related side effects and costs were recorded too.

Results: The mean age in the LIESWT group was 43.7 years old, and in the Tadalafil group was 47 years old. After the 6 and 12-week follow-ups, both groups showed significant improvement when comparing the baseline values to the follow-up variables for all IIEF-5, EHS, and SEAR (P < 0.05). There was a notable statistical difference between the two groups regarding the side effects, as the shockwave group was with mild side effects (8%), while the Tadalafil group (44%) of patients had side effects (p < 0.05). This cost difference is statistically significant (p < 0.001). LIESWT is more costly compared to Tadalafil.

Conclusion: LIESWT has a comparable short-term therapeutic efficacy with higher safety outcomes than on-demand 20 mg of Tadalafil for ED patients.

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低强度体外冲击波治疗与按需他达拉非治疗勃起功能障碍的疗效和安全性。

目的:比较低强度体外冲击波治疗(LIESWT)和20mg他达拉非治疗勃起功能障碍(ED)患者的结果。材料和方法:我们对51例ED患者进行了前瞻性研究。25例在LIESWT组，26例在他达拉非组。LIESWT组患者接受6次(每周2次)，平均每次使用piezowav2单元6000次电击。其他患者根据需要自行服用他达拉非。采用国际勃起功能指数(IIEF-5)评分、勃起硬度评分(EHS)和自尊与关系(SEAR)问卷对治疗前、治疗后6周和12周的结果进行评估。与治疗相关的副作用和费用也被记录下来。结果:LIESWT组患者平均年龄为43.7岁，他达拉非组患者平均年龄为47岁。在6周和12周的随访后，两组患者的IIEF-5、EHS和SEAR的基线值与随访变量比较均有显著改善(P)。结论:LIESWT对ED患者具有相当的短期治疗效果，且安全性高于按需20mg他他拉非。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arab Journal of Urology UROLOGY & NEPHROLOGY-

CiteScore

2.80

自引率

0.00%

发文量

期刊介绍： The Arab Journal of Urology is a peer-reviewed journal that strives to provide a high standard of research and clinical material to the widest possible urological community worldwide. The journal encompasses all aspects of urology including: urological oncology, urological reconstructive surgery, urodynamics, female urology, pediatric urology, endourology, transplantation, erectile dysfunction, and urinary infections and inflammations. The journal provides reviews, original articles, editorials, surgical techniques, cases reports and correspondence. Urologists, oncologists, pathologists, radiologists and scientists are invited to submit their contributions to make the Arab Journal of Urology a viable international forum for the practical, timely and state-of-the-art clinical urology and basic urological research.