Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia.

Journal of fungi (Basel, Switzerland) Pub Date : 2022-10-26 DOI:10.3390/jof8111126

Nishanthinie Thatchanamoorthy, Velayuthan Rukumani Devi, Samudi Chandramathi, Sun Tee Tay

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引用次数: 13

Abstract

Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortality rates in healthcare facilities worldwide. Since its first isolation, the occurrence of C. auris in six continents has becomes a grave concern for the healthcare professionals and scientific community. Recent reports showed the identification of five geographically distinct clades and high rates of antifungal resistance associated with C. auris. Till date, there are no effective treatment options, and standardized measures for prevention and control of C. auris infection in healthcare facilities. This leads to frequent therapeutic failures and complicates the eradication of C. auris infection in healthcare facilities. Thus, this review focuses on the recent understanding of the epidemiology, risk factors, diagnosis, transmission and prevention and control strategies of C. auris infection in healthcare facilities in Asia.

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耳念珠菌:亚洲卫生保健机构流行病学综述。

耳念珠菌是一种新出现的与医疗保健相关的酵母病原体，来自Metschnikowiaceae家族，于2009年首次在一位日本老年患者的耳道中被描述。酵母菌是念珠菌病的病原体之一，念珠菌病与全世界医疗机构的院内暴发和高死亡率有关。自首次分离以来，金黄色葡萄球菌在六大洲的发生已成为卫生保健专业人员和科学界的严重关切。最近的报告显示，鉴定出五个地理上不同的分支，并且与金黄色葡萄球菌相关的抗真菌耐药率很高。迄今为止，在卫生保健机构中没有有效的治疗选择和预防和控制耳念珠菌感染的标准化措施。这导致治疗经常失败，并使卫生保健机构根除耳念珠菌感染复杂化。因此，本文就亚洲医疗机构中auris感染的流行病学、危险因素、诊断、传播和防控策略等方面的最新研究进展进行综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of fungi (Basel, Switzerland)

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