{"title":"Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses.","authors":"Tatsuya Mimura, Hiroshi Fujishima, Eichi Uchio, Kazumi Fukagawa, Yuji Inoue, Makoto Kawashima, Kazuma Kitsu, Atsushi Mizota","doi":"10.2147/OPTO.S381763","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Asian dust poses a serious global health hazard. Airborne particles adhering to contact lenses may cause substantial damage to the ocular surface. The recently released one-day disposable silicone hydrogel soft contact lens (SCL), the verofilcon A, has a smooth surface with SMARTSURFACE<sup>®</sup> technology, which is designed to prevent adhesion of protein components and foreign bodies. The purpose of this study was to verify the protective quality of verofilcon A SCL against adhesion of Asian dust particles to its surface.</p><p><strong>Methods: </strong>Verofilcon A and etafilcon A (control lens) SCLs were used (n=16 per group), and 0.2 mL of physiological saline containing 0.01 mg/mL of Asian dust particles was dropped on the surface of SCLs, allowed to stand for 1 hour, shaken for 1 minute, and rinsed three times with saline (after rinsing). In addition, the samples were agitated by a vortex mixer for 1 minute and rinsed three times with saline (after vortex). The number of Asian dust particles adhering to the SCLs and percentage of the surface area occupied by the Asian dust particles was determined before washing, after rinsing, and after vortexing.</p><p><strong>Results: </strong>The number of adherent Asian dust particles was lower on verofilcon A SCL (297 ± 116 after rinsing, and 5 ± 14 after vortexing) than on etafilcon A SCL (523 ± 212 after rinsing, p=0.003, and 378 ± 268 after vortexing, p<0.001). The Asian dust adhesion area was also lower on verofilcon A SCL (3.6 ± 2.3% after rinsing and 0.0 ± 0.1% after vortexing than on etafilcon A (10.2 ± 2.1% after rinsing, p=0.002, and 5.2 ± 3.0% after vortexing, p<0.001).</p><p><strong>Conclusion: </strong>These findings indicate that verofilcon A SCL has the property of low adhesion of Asian dust particles. Verofilcon A SCL can be recommended for SCL wearers during windy and Asian dust days.</p>","PeriodicalId":43701,"journal":{"name":"Clinical Optometry","volume":" ","pages":"215-221"},"PeriodicalIF":1.8000,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/77/14/opto-14-215.PMC9624171.pdf","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Optometry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OPTO.S381763","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
Purpose: Asian dust poses a serious global health hazard. Airborne particles adhering to contact lenses may cause substantial damage to the ocular surface. The recently released one-day disposable silicone hydrogel soft contact lens (SCL), the verofilcon A, has a smooth surface with SMARTSURFACE® technology, which is designed to prevent adhesion of protein components and foreign bodies. The purpose of this study was to verify the protective quality of verofilcon A SCL against adhesion of Asian dust particles to its surface.
Methods: Verofilcon A and etafilcon A (control lens) SCLs were used (n=16 per group), and 0.2 mL of physiological saline containing 0.01 mg/mL of Asian dust particles was dropped on the surface of SCLs, allowed to stand for 1 hour, shaken for 1 minute, and rinsed three times with saline (after rinsing). In addition, the samples were agitated by a vortex mixer for 1 minute and rinsed three times with saline (after vortex). The number of Asian dust particles adhering to the SCLs and percentage of the surface area occupied by the Asian dust particles was determined before washing, after rinsing, and after vortexing.
Results: The number of adherent Asian dust particles was lower on verofilcon A SCL (297 ± 116 after rinsing, and 5 ± 14 after vortexing) than on etafilcon A SCL (523 ± 212 after rinsing, p=0.003, and 378 ± 268 after vortexing, p<0.001). The Asian dust adhesion area was also lower on verofilcon A SCL (3.6 ± 2.3% after rinsing and 0.0 ± 0.1% after vortexing than on etafilcon A (10.2 ± 2.1% after rinsing, p=0.002, and 5.2 ± 3.0% after vortexing, p<0.001).
Conclusion: These findings indicate that verofilcon A SCL has the property of low adhesion of Asian dust particles. Verofilcon A SCL can be recommended for SCL wearers during windy and Asian dust days.
目的:亚洲粉尘对全球健康构成严重危害。空气中的微粒附着在隐形眼镜上可能会对眼表造成严重损害。最近发布的一次性硅胶水凝胶软性隐形眼镜(SCL) verofilcon A采用SMARTSURFACE®技术,具有光滑的表面,旨在防止蛋白质成分和异物的粘附。本研究的目的是验证verofilcon A SCL对亚洲尘埃颗粒粘附在其表面的保护质量。方法:采用Verofilcon A和etafilcon A(对照镜)scl(每组16例),取含0.01 mg/mL亚洲粉尘颗粒的生理盐水0.2 mL滴于scl表面,静置1小时,摇摇1分钟,用生理盐水冲洗3次(冲洗后)。另外,将样品用涡流混合器搅拌1分钟,用生理盐水冲洗3次(涡流后)。在洗涤前、漂洗后和涡旋后,测定了附着在scl上的亚洲尘埃颗粒的数量和亚洲尘埃颗粒所占表面积的百分比。结果:verofilcon A SCL的亚洲尘粒粘附数(冲洗后为297±116个,旋流后为5±14个)低于etafilcon A SCL(冲洗后为523±212个,p=0.003,旋流后为378±268个)。结论:verofilcon A SCL具有低亚洲尘粒粘附特性。在多风和亚洲沙尘天气,推荐使用Verofilcon A型SCL。
期刊介绍:
Clinical Optometry is an international, peer-reviewed, open access journal focusing on clinical optometry. All aspects of patient care are addressed within the journal as well as the practice of optometry including economic and business analyses. Basic and clinical research papers are published that cover all aspects of optics, refraction and its application to the theory and practice of optometry. Specific topics covered in the journal include: Theoretical and applied optics, Delivery of patient care in optometry practice, Refraction and correction of errors, Screening and preventative aspects of eye disease, Extended clinical roles for optometrists including shared care and provision of medications, Teaching and training optometrists, International aspects of optometry, Business practice, Patient adherence, quality of life, satisfaction, Health economic evaluations.