Transcutaneous vagus nerve stimulation and the realm of its therapeutic hopes and physiologic enigmas

IF 3.2 4区医学 Q2 NEUROSCIENCES

Autonomic Neuroscience-Basic & Clinical Pub Date : 2022-12-01 DOI:10.1016/j.autneu.2022.103039

Max J. Hilz , Armin Bolz

引用次数: 3

Abstract

Vagus nerve stimulation (VNS) is an established treatment option for patients with treatment resistant epilepsy and depression. However, the procedure is invasive and has side-effects. Transcutaneous vagus nerve stimulation (tVNS) is a non-invasive alternative. Particularly transcutaneous stimulation at the outer ear is gaining increasing interest. While the scope of therapeutic tVNS applications is expanding, there are still questions regarding the optimal stimulation parameters and site as well as the physiology and pathways of auricular tVNS. This Special Issue of Autonomic Neuroscience: Basic & Clinical provides an introduction and overview on basic aspects as well as special topics of tVNS.

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经皮迷走神经刺激及其治疗希望和生理谜团的领域

迷走神经刺激(VNS)是治疗难治性癫痫和抑郁症患者的既定治疗选择。然而，这个过程是侵入性的，并且有副作用。经皮迷走神经刺激(tVNS)是一种无创的替代方法。特别是外耳经皮刺激法正获得越来越多的关注。虽然治疗性tVNS的应用范围正在扩大，但关于最佳刺激参数和部位以及耳穴tVNS的生理和通路仍然存在疑问。《自主神经科学:基础》特刊临床介绍和概述了tVNS的基本方面以及专题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Autonomic Neuroscience-Basic & Clinical 医学-神经科学

CiteScore

5.80

自引率

7.40%

发文量

审稿时长

66 days

期刊介绍： This is an international journal with broad coverage of all aspects of the autonomic nervous system in man and animals. The main areas of interest include the innervation of blood vessels and viscera, autonomic ganglia, efferent and afferent autonomic pathways, and autonomic nuclei and pathways in the central nervous system. The Editors will consider papers that deal with any aspect of the autonomic nervous system, including structure, physiology, pharmacology, biochemistry, development, evolution, ageing, behavioural aspects, integrative role and influence on emotional and physical states of the body. Interdisciplinary studies will be encouraged. Studies dealing with human pathology will be also welcome.