The comparison of endothelial function of moderate intensity interval exercise with continuous exercise in healthy men

IF 2.1 Q3 PHYSIOLOGY
Burcu Meri̇c , Serdar Solak , Nurettin Aydogdu , Necdet Sut , Selma Arzu Vardar
{"title":"The comparison of endothelial function of moderate intensity interval exercise with continuous exercise in healthy men","authors":"Burcu Meri̇c ,&nbsp;Serdar Solak ,&nbsp;Nurettin Aydogdu ,&nbsp;Necdet Sut ,&nbsp;Selma Arzu Vardar","doi":"10.1016/j.crphys.2022.07.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Background/aim</h3><p>Exercise enhances endothelium-dependent vasodilation; however, it is unclear whether intermittent exercise has a different effect on vascular endothelial function compared to continuous exercise. This study aimed to compare vascular endothelial function following intermittent exercise including short rest intervals with continuous exercise, both at the anaerobic threshold level.</p></div><div><h3>Materials and methods</h3><p>Peak oxygen consumption (VO<sub>2</sub> peak) and anaerobic threshold were measured in physically active healthy young men (n = 12) by breath-by-breath analysis. After completion of intermittent exercise consisting of eight 1-min long intervals at the anaerobic threshold intensity with 75-s rest periods, total work was calculated. Equivalent work was done during continuous exercise. Immediately after the two exercise periods, venous blood lactate, endothelial nitric oxide synthase (eNOS), endothelin-1, N-terminal proANP (NTproANP), N-terminal proBNP (NTproBNP), and N-terminal proCNP (NTproCNP) levels were measured. Brachial artery flow-mediated dilatation (FMD) was measured before exercise and 30 min after exercise.</p></div><div><h3>Results</h3><p>Mean VO<sub>2</sub> peak level was 33.42 ± 5.9 ml/min/kg and anaerobic threshold level was 47.33 ± 5.85%. Lactate levels following continuous exercise were higher than levels following intermittent exercise (27.76 ± 7.43 mg/dl, 18.54 ± 4.87 mg/dl respectively; p˂0.05). Endothelin-1, eNOS, NTproANP, NTproBNP, and NTproCNP levels were similar after both modalities of exercise (p &gt; 0.05). No significant difference was found in FMD response when comparing intermittent and continuous exercise (7.05 ± 15.11%, 2.49 ± 16.24% respectively; p &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>Since blood lactate levels are higher following continuous exercise, individuals who find difficulty exercising may prefer an intermittent form of exercise. However, both intermittent and continuous exercise at the anaerobic threshold level seem to not produce a significant acute change in endothelial function in healthy men.</p></div>","PeriodicalId":72753,"journal":{"name":"Current research in physiology","volume":"5 ","pages":"Pages 338-343"},"PeriodicalIF":2.1000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2c/8f/main.PMC9307423.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current research in physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2665944122000347","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background/aim

Exercise enhances endothelium-dependent vasodilation; however, it is unclear whether intermittent exercise has a different effect on vascular endothelial function compared to continuous exercise. This study aimed to compare vascular endothelial function following intermittent exercise including short rest intervals with continuous exercise, both at the anaerobic threshold level.

Materials and methods

Peak oxygen consumption (VO2 peak) and anaerobic threshold were measured in physically active healthy young men (n = 12) by breath-by-breath analysis. After completion of intermittent exercise consisting of eight 1-min long intervals at the anaerobic threshold intensity with 75-s rest periods, total work was calculated. Equivalent work was done during continuous exercise. Immediately after the two exercise periods, venous blood lactate, endothelial nitric oxide synthase (eNOS), endothelin-1, N-terminal proANP (NTproANP), N-terminal proBNP (NTproBNP), and N-terminal proCNP (NTproCNP) levels were measured. Brachial artery flow-mediated dilatation (FMD) was measured before exercise and 30 min after exercise.

Results

Mean VO2 peak level was 33.42 ± 5.9 ml/min/kg and anaerobic threshold level was 47.33 ± 5.85%. Lactate levels following continuous exercise were higher than levels following intermittent exercise (27.76 ± 7.43 mg/dl, 18.54 ± 4.87 mg/dl respectively; p˂0.05). Endothelin-1, eNOS, NTproANP, NTproBNP, and NTproCNP levels were similar after both modalities of exercise (p > 0.05). No significant difference was found in FMD response when comparing intermittent and continuous exercise (7.05 ± 15.11%, 2.49 ± 16.24% respectively; p > 0.05).

Conclusion

Since blood lactate levels are higher following continuous exercise, individuals who find difficulty exercising may prefer an intermittent form of exercise. However, both intermittent and continuous exercise at the anaerobic threshold level seem to not produce a significant acute change in endothelial function in healthy men.

Abstract Image

Abstract Image

Abstract Image

健康男性中等强度间歇运动与持续运动对内皮功能的影响
背景/目的运动增强内皮依赖性血管舒张;然而,间歇性运动对血管内皮功能的影响是否与连续运动不同,目前尚不清楚。本研究旨在比较间歇运动(包括短休息时间)和连续运动(均为无氧阈值水平)后血管内皮功能。材料与方法采用呼吸分析方法测定12例身体活跃的健康青年男性的耗氧量(VO2峰值)和无氧阈值。在无氧阈值强度下完成8次1分钟长的间歇运动,休息时间为75秒后,计算总功。在连续运动中做了相当的功。两个运动周期结束后立即测定静脉血乳酸、内皮一氧化氮合酶(eNOS)、内皮素-1、n端proANP (NTproANP)、n端proBNP (NTproBNP)和n端proCNP (NTproCNP)水平。在运动前和运动后30分钟测量肱动脉血流介导扩张(FMD)。结果平均VO2峰值水平为33.42±5.9 ml/min/kg,无氧阈值为47.33±5.85%。连续运动后的乳酸水平高于间歇运动后的乳酸水平(分别为27.76±7.43 mg/dl、18.54±4.87 mg/dl);p˂0.05)。两种运动方式后,内皮素-1、eNOS、NTproANP、NTproBNP和NTproCNP水平相似(p >0.05)。间歇运动与连续运动的FMD反应无显著差异(分别为7.05±15.11%、2.49±16.24%);p比;0.05)。结论:由于持续运动后血乳酸水平较高,因此发现运动困难的个体可能更喜欢间歇性运动。然而,在无氧阈值水平下的间歇和连续运动似乎不会对健康男性的内皮功能产生显著的急性变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.20
自引率
0.00%
发文量
0
审稿时长
62 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信