Fatty Acid Taste Receptor GPR120 Activation by Arachidonic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid in Chickens.

IF 1.8 4区农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Journal of Poultry Science Pub Date : 2022-07-25 DOI:10.2141/jpsa.0210099

Fuminori Kawabata, Yuta Yoshida, Seiga Kuba, Yuko Kawabata, Shotaro Nishimura, Shoji Tabata

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引用次数: 1

Abstract

It has been reported that the supplementation of chicken diet with polyunsaturated fatty acids (PUFAs) such as arachidonic acid (AA), eicosapentaenoic acid (EPA), or docosahexaenoic acid (DHA) affects the qualities of eggs and meat. Previous studies have shown that a functional fatty acid taste receptor, G protein-coupled receptor 120 (GPR120), is broadly expressed in chicken oral and gastrointestinal tissues, and chickens have a gustatory perception of oleic acid, which is a chicken GPR120 agonist. The aim of this study was to elucidate the role of chicken GPR120 in response to PUFAs in chicken diets. Ca²⁺ imaging analyses revealed that chicken GPR120 was activated by AA, EPA, and DHA in a concentration-dependent manner. These results suggest that chickens can detect PUFAs via GPR120 in the oral and gastrointestinal tissues, implying that chickens have a gustatory perception of PUFAs.

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花生四烯酸、二十碳五烯酸和二十二碳六烯酸对鸡脂肪酸味觉受体GPR120的激活作用

有报道称，在鸡粮中添加花生四烯酸(AA)、二十碳五烯酸(EPA)或二十二碳六烯酸(DHA)等多不饱和脂肪酸(PUFAs)会影响蛋和肉的品质。先前的研究表明，一种功能性脂肪酸味觉受体G蛋白偶联受体120 (GPR120)在鸡口腔和胃肠道组织中广泛表达，鸡对油酸具有味觉感知，油酸是鸡GPR120的激动剂。本研究的目的是阐明鸡GPR120在鸡日粮中对PUFAs的响应中的作用。Ca2+成像分析显示，鸡GPR120被AA、EPA和DHA以浓度依赖性的方式激活。这些结果表明，鸡可以通过口腔和胃肠道组织中的GPR120检测到PUFAs，这表明鸡对PUFAs具有味觉感知能力。

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来源期刊

Journal of Poultry Science AGRICULTURE, DAIRY & ANIMAL SCIENCE-

CiteScore

2.80

自引率

13.30%

发文量

审稿时长

12 months

期刊介绍： The Journal of Poultry Science will publish original reports and reviews which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: breeding and genetics, nutrition and feeds, physiology, reproduction, immunology, behavior, environmental science, management and housing welfare, processing and products, and health in poultry. Submission of original articles to the Journal is open to all poultry researchers. The review articles are invited papers written by international outstanding researchers. Articles will be published in English, American style.