Evaluation of maximal exercise capacity through the incremental shuttle walking test in lymphangioleiomyomatosis

IF 10.4 2区医学 Q1 RESPIRATORY SYSTEM

Pulmonology Pub Date : 2024-11-01 DOI:10.1016/j.pulmoe.2022.04.009

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引用次数: 0

Abstract

Background

The cardiopulmonary exercise test (CPET) is the gold standard for assessing aerobic fitness; however, it is expensive, not widely available, and requires specialized equipment and staff. The incremental shuttle walking test (ISWT) is an exercise field test used to evaluate exercise capacity and may be an alternative to CPET in patients with lymphangioleiomyomatosis (LAM).

Objective

To investigate whether the ISWT can be used to assess maximal aerobic capacity in patients with LAM.

Methods

Forty-five women were evaluated on two days, and they randomly performed the CPET and ISWT. The maximum oxygen uptake (peak VO₂) was evaluated using gas analyzers in both tests. The carbon dioxide production (VCO₂), respiratory exchange ratio (RER), and heart rate (HR) were compared during peak exercise. Pearson's correlation and Bland-Altman assessed the association and agreement, respectively. The intraclass correlation coefficient (ICC) was used to assess the reliability of the data.

Results

All patients (46.1 ± 10.2 years) presented similar peak VO₂, RER, and peak HR during the CPET and ISWT (15.6 ± 4.6 vs. 15.7 ± 4.4 ml·kg⁻¹·min⁻¹; 1.15±0.09 vs. 1.17±0.12; and 142.2 ± 18.6 vs. 141.5 ± 22.2 bpm, respectively; p>0.05). A good linear correlation (r = 0.79; p<0.001) and ICC (0.86; 95%CI 0.74−0.93) were observed between the peak VO₂ in both tests. Predictive peak VO₂ equations based on the ISWT performance are also presented.

Conclusion

Our results suggest that the ISWT can be used to assess maximal exercise performance in patients with LAM, and it is a valuable option to be used as an alternative to the CPET and predict maximal exercise capacity.

查看原文本刊更多论文

通过增量穿梭步行测试评估淋巴管瘤病的最大运动能力。

背景：心肺运动测试（CPET）是评估有氧体能的黄金标准；然而，它价格昂贵，并不普及，而且需要专门的设备和人员。增量穿梭步行试验（ISWT）是一种用于评估运动能力的运动场试验，可作为淋巴管瘤病患者 CPET 的替代方法：目的：研究 ISWT 是否可用于评估 LAM 患者的最大有氧能力：方法：45 名女性在两天内接受了评估，她们随机进行了 CPET 和 ISWT。两项测试均使用气体分析仪评估最大摄氧量（峰值 VO2）。比较了峰值运动时的二氧化碳产生量（VCO2）、呼吸交换比（RER）和心率（HR）。Pearson 相关性和 Bland-Altman 分别评估了相关性和一致性。类内相关系数（ICC）用于评估数据的可靠性：结果：所有患者（46.1±10.2 岁）在 CPET 和 ISWT 过程中的峰值 VO2、RER 和峰值 HR 相似（分别为 15.6±4.6 vs. 15.7±4.4 ml-kg-1-min-1；1.15±0.09 vs. 1.17±0.12；142.2±18.6 vs. 141.5±22.2 bpm；P>0.05）。两项测试的线性相关性良好（r = 0.79；p2）。结论：我们的研究结果表明，ISWT 是一种有效的运动疗法：我们的研究结果表明，ISWT 可用于评估 LAM 患者的最大运动能力，是替代 CPET 和预测最大运动能力的重要选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pulmonology Medicine-Pulmonary and Respiratory Medicine

CiteScore

14.30

自引率

5.10%

发文量

159

审稿时长

19 days

期刊介绍： Pulmonology (previously Revista Portuguesa de Pneumologia) is the official journal of the Portuguese Society of Pulmonology (Sociedade Portuguesa de Pneumologia/SPP). The journal publishes 6 issues per year and focuses on respiratory system diseases in adults and clinical research. It accepts various types of articles including peer-reviewed original articles, review articles, editorials, and opinion articles. The journal is published in English and is freely accessible through its website, as well as Medline and other databases. It is indexed in Science Citation Index Expanded, Journal of Citation Reports, Index Medicus/MEDLINE, Scopus, and EMBASE/Excerpta Medica.