The role of inflammation in percutaneous coronary intervention, from balloon angioplasty to drug eluting stents.

IF 1.4 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Minerva cardiology and angiology Pub Date : 2023-12-01 Epub Date: 2022-07-05 DOI:10.23736/S2724-5683.22.06091-4
Ioannis Merinopoulos, Tharusha Gunawardena, Natasha Corballis, Vassiliki Tsampasian, Simon C Eccleshall, James Smith, Vassilios S Vassiliou
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引用次数: 0

Abstract

The role of inflammation in percutaneous coronary intervention (PCI) has been investigated in numerous studies. Both pre-PCI and post-PCI inflammatory status have been demonstrated to be linked with patient outcomes. C-reactive protein continues to be the most studied inflammatory biomarker, while a growing number of additional biomarkers, including cytokines and immune cells, are being assessed. As insights are gained into the complexities of the inflammatory response to PCI, it becomes evident that a targeted approach is necessary to ensure optimal patient outcomes. Here, we review the biomarkers that can predict patient outcomes following PCI and specifically how they differ for balloon angioplasty, bare metal stents and drug eluting stents. A specific focus is given to human studies and periprocedural inflammation rather than inflammation associated with myocardial infarction.

炎症在经皮冠状动脉介入治疗中的作用,从球囊血管成形术到药物洗脱支架。
炎症在经皮冠状动脉介入治疗(PCI)中的作用已被大量研究探讨。pci术前和pci后的炎症状态已被证明与患者预后相关。c反应蛋白仍然是研究最多的炎症生物标志物,同时越来越多的其他生物标志物,包括细胞因子和免疫细胞,正在被评估。随着对PCI炎症反应复杂性的深入了解,很明显,有针对性的方法是确保患者获得最佳结果的必要条件。在这里,我们回顾了可以预测PCI后患者预后的生物标志物,特别是球囊血管成形术、裸金属支架和药物洗脱支架的差异。一个特定的重点是人类研究和手术期间的炎症,而不是与心肌梗死相关的炎症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Minerva cardiology and angiology
Minerva cardiology and angiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
18.80%
发文量
118
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