Low-Dose NSAIDs Efficacy in Orthopedic Applications.

IF 2.5 4区医学 Q2 SPORT SCIENCES

Sports Medicine and Arthroscopy Review Pub Date : 2022-09-01 Epub Date: 2022-08-03 DOI:10.1097/JSA.0000000000000353

Francesco Oliva, Marco Quaranta, Lucio Cipollaro, Valeria Conti, Emanuela De Bellis, Amelia Filippelli, Nicola Maffulli

引用次数: 0

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) [cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors] and COXIBs (the COX-2 selective inhibitors) may induce several potentially severe and life-threatening issues especially in elderly patients. The use of low-dose NSAIDs is associated with lower risk of side effects compared to the standard dosage. Low-dose NSAIDs could minimize the side effects of these drugs while maintaining their clinical efficacy and effectiveness. The present study evaluates the effectiveness and safety of low-dose NSAIDs in musculoskeletal applications.

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低剂量非甾体抗炎药在骨科应用中的疗效。

非甾体抗炎药(NSAIDs)[环氧化酶-1 (COX-1)和环氧化酶-2 (COX-2)抑制剂]和coxib (COX-2选择性抑制剂)可能诱发一些潜在的严重和危及生命的问题，特别是在老年患者中。与标准剂量相比，使用低剂量非甾体抗炎药的副作用风险更低。低剂量非甾体抗炎药可以在保持其临床疗效的同时，最大限度地减少这些药物的副作用。本研究评估了低剂量非甾体抗炎药在肌肉骨骼应用中的有效性和安全性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sports Medicine and Arthroscopy Review 医学-运动科学

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Sports Medicine and Arthroscopy Review helps physicians digest the large volume of clinical literature in sports medicine and arthroscopy, identify the most important new developments, and apply new information effectively in clinical practice. Each issue is guest-edited by an acknowledged expert and focuses on a single topic or controversy. The Guest Editor invites the leading specialists on the topic to write review articles that highlight the most important advances. This unique format makes the journal more in-depth, authoritative, and practical than most publications in this field. The journal also includes dozens of full-color and black-and-white arthroscopic images and illustrations.

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