Bridging the gap between science and society: long-term effects of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on weight and the metabolic risk profile: a controlled study.

IF 3.3 Q2 NUTRITION & DIETETICS
BMJ Nutrition, Prevention and Health Pub Date : 2022-02-22 eCollection Date: 2022-01-01 DOI:10.1136/bmjnph-2021-000340
Corinna Anand, Ragna-Marie Kranz, Sarah Husain, Christian Koeder, Nora Schoch, Dima-Karam Alzughayyar, Reinhold Gellner, Karin Hengst, Heike Englert
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引用次数: 4

Abstract

Background: The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control.

Methods: 24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted.

Results: 143 participants (58±12 years, 71% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups' baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by -1.5 ± 1.9 kg after 8 weeks to -1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a 'high' adherence (+12%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve.

Conclusion: The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk.

Trial registration number: DRKS00018821.

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弥合科学与社会之间的差距:健康生活方式社区计划(HLCP,队列1)对体重和代谢风险概况的长期影响:一项对照研究。
背景:采用健康的生活方式来防治非传染性疾病的潜力尚未得到充分利用。我们假设,与基线和对照组相比,健康生活方式社区计划(HLCP,队列1)降低了体重和其他风险指标。方法:为期24个月的非随机对照干预试验。干预:密集的8周阶段,包括研讨会、讲习班和指导,重点是健康的生活方式(例如,植物性饮食、体育活动、压力管理)和小组支持,随后是22个月的校友阶段。在6个时间点评估体重减轻作为主要结局和其他非传染性疾病风险参数。参与者是从普通人群中招募的。进行多元线性回归分析。结果:共纳入143例(58±12岁,71%为女性),其中干预组(IG) 91例,对照组(CG) 52例。各组的基线特征具有可比性,除了IG的参与者更年轻,更常见的是女性,超重和报告的能量摄入(千卡/天)较低。在所有随访中,IG组的体重在8周后显著下降-1.5±1.9 kg,在24个月后显著下降-1.9±4.0 kg,并且比CG组下降更多(24个月后除外)。男性,在IG或超重基线和拥有大学学位预测更多的体重减轻。干预后,IG中有更多的参与者对植物性食物模式的“高”依从性(+12%)。其他风险参数的变化在8周后和高风险人群中最为明显。糖尿病相关的风险参数没有改善。结论:HLCP能够减轻体重并改善非传染性疾病风险概况。大鼠体重减轻幅度不大,但持续了24个月。教育程度较低的参与者可能会从更实用的单元中受益。未来的干预措施应旨在包括更多的高风险参与者。试验注册号:DRKS00018821。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Nutrition, Prevention and Health
BMJ Nutrition, Prevention and Health Nursing-Nutrition and Dietetics
CiteScore
5.80
自引率
0.00%
发文量
34
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