Effects of Covid-19 vaccination on different semen parameters.

IF 2.4 3区医学 Q2 ANDROLOGY

Basic and Clinical Andrology Pub Date : 2022-08-02 DOI:10.1186/s12610-022-00163-x

Ziad H Abd, Samir A Muter, Ruya Abdulhadi M Saeed, Omar Ammar

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引用次数: 9

Abstract

Background: The possible effects of COVID-19 vaccines on reproductive health and male fertility in particular have been discussed intensely by the scientific community and the public since their introduction during the pandemic. On news outlets and social media platforms, many claims have been raised regarding the deleterious effects of COVID-19 vaccines on sperm quality without scientific evidence. In response to this emerging conflict, we designed this study to evaluate and assess the effect of the Pfizer-BioNTech mRNA COVID-19 vaccine on male fertility represented by the semen analysis parameters.

Results: Comparing the semen parameters of the participants before and after vaccination, no statistically significant effects on semen volume, pH or normal sperm concentration and morphology were shown. However, there were statistically significant differences on total sperm motility (P = 0.05) and progressive motility (P = 0.02). These differences are clinically insignificant given the fact that both readings before and after vaccination were within the normal ranges, according to the WHO manual guidelines for the examination and processing of human semen.

Conclusion: Our data suggest that the Pfizer-BioNTech mRNA COVID-19 vaccine has no deleterious effects on semen parameters.

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新型冠状病毒疫苗接种对不同精液参数的影响

背景:自COVID-19疫苗在大流行期间引入以来，科学界和公众一直在激烈讨论疫苗对生殖健康和男性生育能力的可能影响。在新闻媒体和社交媒体平台上，许多人在没有科学证据的情况下提出了关于COVID-19疫苗对精子质量有害的说法。针对这一新出现的冲突，我们设计了本研究，以精液分析参数为代表，评估辉瑞- biontech mRNA COVID-19疫苗对男性生育能力的影响。结果:比较接种前后受试者精液参数，对精液体积、pH值、正常精子浓度和形态均无显著影响。总精子活力(P = 0.05)和进行性精子活力(P = 0.02)差异有统计学意义。鉴于根据世卫组织人类精液检查和处理手册指南，接种疫苗前后的读数均在正常范围内，这些差异在临床上并不显著。结论:我们的数据表明，辉瑞- biontech mRNA COVID-19疫苗对精液参数没有有害影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Basic and Clinical Andrology Medicine-Urology

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

22 weeks

期刊介绍： Basic and Clinical Andrology is an open access journal in the domain of andrology covering all aspects of male reproductive and sexual health in both human and animal models. The journal aims to bring to light the various clinical advancements and research developments in andrology from the international community.