The role of sense of coherence and loneliness in borderline personality disorder traits: a longitudinal twin study.

IF 4 2区 医学 Q1 PSYCHIATRY
Eirunn Skaug, Nikolai O Czajkowski, Trine Waaktaar, Svenn Torgersen
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引用次数: 2

Abstract

Background: Borderline personality disorder (BPD) implies having problems with identity and relations with other people. However, not much is known about whether these indications of BPD are present in adolescence, i.e., before personality disorders usually are diagnosed. In this study, we examined the prediction of an aspect of identity (i.e., sense of coherence [SOC]) and social relations (i.e., perceived loneliness) throughout adolescence on BPD traits in young adulthood. In addition, we examined to what degree the predictive ability could be attributed to genetic and environmental factors. We also examined whether life events in adolescence were related to BPD traits.

Methods: Three thousand three hundred ninety-one twins, consisting of seven national birth cohorts from Norway, participated in the study. SOC, loneliness and life events were measured three times throughout adolescence with self-report questionnaires, with 2 years in between measurements. BPD traits were measured at the end of adolescence around the age of 19 with a structured interview. Regression analyses were performed to examine the prediction of SOC, loneliness and life events on BPD traits. Cholesky decomposition models were then used to determine to what degree the associations were due to genetic and environmental influences.

Results: The prediction of SOC and loneliness on BPD traits increased from R = .25 (when measured 6 years prior to the assessment of BPD traits) to R = .45 (when measured shortly before the assessment of BPD traits). In addition, negative life events considered dependent on a person's behavior were related to BPD traits. Negative independent and positive dependent life events did not contribute to the prediction of BPD traits. Cholesky decomposition models showed that SOC and loneliness were associated with BPD traits mainly due to shared genetic influences (i.e., the proportion due to genetic influences ranged from 71 to 86%). Adding negative dependent life events to the prediction of BPD traits did not change these percentages.

Conclusions: These findings indicate that the weaker SOC, the stronger feelings of loneliness, and the negative life events associated with BPD traits are mainly consequences of the genetic aspects of BPD traits, rather than having direct effects on levels of BPD symptoms.

Abstract Image

连贯性感和孤独感在边缘型人格障碍特征中的作用:一项纵向双胞胎研究。
背景:边缘型人格障碍(BPD)意味着在身份认同和与他人的关系方面存在问题。然而,在人格障碍通常被诊断出来之前,这些BPD的症状是否存在于青春期,我们所知不多。在本研究中,我们考察了整个青春期的身份(即连贯感[SOC])和社会关系(即感知孤独)对青年期BPD特征的预测。此外,我们还研究了遗传和环境因素对预测能力的影响程度。我们还研究了青春期的生活事件是否与BPD特征有关。方法:来自挪威的7个国家出生队列的3391对双胞胎参与了这项研究。在整个青春期,SOC、孤独感和生活事件用自我报告问卷进行了三次测量,两次测量之间间隔2年。BPD特征是在19岁左右的青春期结束时通过结构化访谈进行测量的。采用回归分析研究SOC、孤独感和生活事件对BPD特征的预测作用。然后使用乔列斯基分解模型来确定这种关联在多大程度上是由于遗传和环境的影响。结果:SOC和孤独感对BPD性状的预测从R = 0.25上升(在评估BPD特征前6年测量)至R = 0.45(在评估BPD特征前不久测量)。此外,被认为依赖于个人行为的负面生活事件与BPD特征有关。消极独立生活事件和积极依赖生活事件对BPD特征的预测没有影响。Cholesky分解模型显示,SOC和孤独感与BPD特征的关联主要是由于共同的遗传影响(即遗传影响的比例为71% ~ 86%)。在BPD特征预测中加入负性依赖生活事件并没有改变这些百分比。结论:这些研究结果表明,与BPD特征相关的较弱的SOC、较强的孤独感和负面生活事件主要是BPD特征遗传方面的结果,而不是直接影响BPD症状的水平。
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来源期刊
CiteScore
6.00
自引率
9.80%
发文量
30
审稿时长
28 weeks
期刊介绍: Borderline Personality Disorder and Emotion Dysregulation provides a platform for researchers and clinicians interested in borderline personality disorder (BPD) as a currently highly challenging psychiatric disorder. Emotion dysregulation is at the core of BPD but also stands on its own as a major pathological component of the underlying neurobiology of various other psychiatric disorders. The journal focuses on the psychological, social and neurobiological aspects of emotion dysregulation as well as epidemiology, phenomenology, pathophysiology, treatment, neurobiology, genetics, and animal models of BPD.
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