Increased future liver function after modified associating liver partition and portal vein ligation/embolization for staged hepatectomy.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Acta radiologica open Pub Date : 2022-10-18 eCollection Date: 2022-10-01 DOI:10.1177/20584601221134951

Mitsunari Maruyama, Takeshi Yoshizako, Rika Yoshida, Megumi Nakamura, Yoshitsugu Tajima, Hajime Kitagaki

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引用次数: 0

Abstract

Background: The increasing ratio of functional future liver remnant (functional %FLR) after modified associating liver partition and portal vein ligation/embolization for staged hepatectomy (modified-ALPPS) compared with portal vein embolization (PVE) has not been comprehensively evaluated.

Purpose: To compare the increasing ratio of functional %FLR between modified-ALPPS and PVE via technetium-99 m-galactosyl human serum albumin single-photon emission computed tomography (^99mTc-GSA SPECT/CT) fusion imaging.

Material and methods: Seven and six patients underwent modified-ALPPS (modified-ALPPS group) and PVE (PVE group) from 2015 to 2019. The functional %FLR on 99 mTc-GSA SPECT/CT fusion imaging was assessed before and 1 week (modified-ALPPS group) and 3 weeks (PVE group) after each procedure. The increasing ratio of functional %FLR (functional %FLR ratio) was calculated and compared between the two groups. Moreover, the hypertrophy ratio of future liver remnant volume (FLRV ratio) and atrophy ratio of embolized liver volume (.ELV ratio) were evaluated.

Results: The mean functional %FLR ratios of the modified-ALPPS group (1.47 ± 0.15) and the PVE group (1.49 ± 0.20) were comparable (p > .05). The median FLRV ratio of modified-ALPPS group (1.48) was higher than that of the PVE group (1.16), the median ELV ratio of the PVE group (0.81) was lower than that of the modified-ALPPS group (0.94), and the results significantly differed between the two groups (p < .05).

Conclusion: The increasing ratio of functional %FLR was comparable between modified-ALPPS and PVE. Compared with PVE, ALPPS was associated with a higher hypertrophy rate of the remnant liver but a lower atrophy rate of the embolized liver.

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改良联合肝分区和门静脉结扎/栓塞后分期肝切除术后肝功能增加。

背景:与门静脉栓塞(PVE)相比，改良联合肝分割和门静脉结扎/栓塞分期肝切除术(modified- alpps)后功能性未来肝残余(functional %FLR)的增加率尚未得到全面评估。目的:通过技术-99 m-半乳糖人血清白蛋白单光子发射计算机断层扫描(99mTc-GSA SPECT/CT)融合成像，比较改良alpps与PVE的功能性%FLR增加率。材料与方法:2015 - 2019年分别有7例和6例患者接受了改良alpps(改良alpps组)和PVE (PVE组)治疗。在每次手术前、1周(改良alpps组)和3周(PVE组)评估99mtc - gsa SPECT/CT融合成像的功能%FLR。计算并比较两组功能性%FLR的增加比率(functional %FLR ratio)。未来残肝体积肥大比(FLRV ratio)和栓塞后肝体积萎缩比(FLRV ratio)。ELV比率)。结果:改良alpps组(1.47±0.15)与PVE组(1.49±0.20)的平均功能%FLR比具有可比性(p > 0.05)。改良alpps组FLRV比中位数(1.48)高于改良alpps组(1.16)，ELV比中位数(0.81)低于改良alpps组(0.94)，两组结果差异有统计学意义(p < 0.05)。结论:改良alpps与PVE的功能性%FLR增加率具有可比性。与PVE相比，ALPPS与残余肝的肥厚率较高，但栓塞肝的萎缩率较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Acta radiologica open

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12 weeks